Results 71 to 80 of about 12,613 (178)

Membrane Guanylate Cyclase catalytic Subdomain: Structure and Linkage with Calcium Sensors and Bicarbonate

Frontiers in Molecular Neuroscience, 2017
Membrane guanylate cyclase (MGC) is a ubiquitous multi-switching cyclic GMP generating signaling machine linked with countless physiological processes. In mammals it is encoded by seven distinct homologous genes.
Sarangan Ravichandran, Teresa Duda, Alexandre Pertzev, Rameshwar K. Sharma   +3 more
doaj   +1 more source

Mixed Palettes of Melanopsin Phototransduction [PDF]

Cell, 2018
Animal photoreceptors divide into two fundamental classes, ciliary and rhabdomeric. Jiang and colleagues demonstrate that this boundary is disregarded by the intrinsically photosensitive retinal ganglion cells of mammals. These neurons draw from phototransduction mechanisms of both classes, enriching the signals that they produce to drive a diversity ...
openaire   +2 more sources

Progressive mitochondrial dysfunction impairs visual signal transduction and induces retinal degeneration in Drosophila

Frontiers in Insect Science
Mitochondrial dysfunction is closely associated with the pathogenesis of retinitis pigmentosa (RP), often through the generation of reactive oxygen species (ROS), which disrupts visual signal transduction.
Jinguo Cao, Yining Li, Xiaohui Hu, Zhaoqi Wu, Jiting Zhang, Yue Zhou, Wei Luan, Wen Hu, Wen Hu, Jianhong Tang, Jianhong Tang   +10 more
doaj   +1 more source

Phototransduction in ganglion-cell photoreceptors [PDF]

Pflügers Archiv - European Journal of Physiology, 2007
A third class of photoreceptors has recently been identified in the mammalian retina. They are a rare cell type within the class of ganglion cells, which are the output cells of the retina. These intrinsically photosensitive retinal ganglion cells support a variety of physiological responses to daylight, including synchronization of circadian rhythms ...
openaire   +2 more sources

Inherited macular degeneration-associated mutations in CNGB3 increase the ligand sensitivity and spontaneous open probability of cone cyclic nucleotide-gated channels.

Frontiers in Physiology, 2015
Cyclic nucleotide gated (CNG) channels are a critical component of the visual transduction cascade in the vertebrate retina. Mutations in the genes encoding these channels have been associated with a spectrum of inherited retinal disorders.
Peter eMeighan, Changhong ePeng, Michael eVarnum   +2 more
doaj   +1 more source

Corrigendum: Modeling Circadian Phototransduction: Quantitative Predictions of Psychophysical Data

Frontiers in Neuroscience, 2022
Mark S. Rea, Mark S. Rea, Rohan Nagare, Rohan Nagare, Mariana G. Figueiro, Mariana G. Figueiro   +5 more
doaj   +1 more source

Successive requirement of Glass and Hazy for photoreceptor specification and maintenance in Drosophila

Fly, 2017
Development of the insect compound eye requires a highly controlled interplay between transcription factors. However, the genetic mechanisms that link early eye field specification to photoreceptor terminal differentiation and fate maintenance remain ...
F. Javier Bernardo-Garcia, Tim-Henning Humberg, Cornelia Fritsch, Simon G. Sprecher   +3 more
doaj   +1 more source

Maintenance of Rhodopsin levels in Drosophila photoreceptor and phototransduction requires Protein Kinase D

Fly, 2018
During Drosophila phototransduction, the G protein coupled receptor (GPCR) Rhodopsin (Rh1) transduces photon absorption into electrical signal via G-protein coupled activation of phospholipase C (PLC).
Sudipta Ashe, Shweta Yadav
doaj   +1 more source

Dendrobium nobile Polysaccharide Attenuates Blue Light-Induced Injury in Retinal Cells and In Vivo in Drosophila

Antioxidants
Blue light is the higher-energy region of the visible spectrum. Excessive exposure to blue light is known to induce oxidative stress and is harmful to the eyes. The stems of Dendrobium nobile Lindl.
Wei-Hsiang Hsu, Chanikan Sangkhathat, Mei-Kuang Lu, Wei-Yong Lin, Hsin-Ping Liu, Yun-Lian Lin   +5 more
doaj   +1 more source

Corrigendum: Expression of opsins of the box jellyfish Tripedalia cystophora reveals the first photopigment in cnidarian ocelli and supports the presence of photoisomerases

Frontiers in Neuroanatomy, 2022
Anders Garm, Jens-Erik Svaerke, Daniela Pontieri, Todd H. Oakley   +3 more
doaj   +1 more source