Results 61 to 70 of about 12,613 (178)

Cnidocyte discharge is regulated by light and opsin-mediated phototransduction

open access: yesBMC Biology, 2012
Background Cnidocytes, the eponymous cell type of the Cnidaria, facilitate both sensory and secretory functions and are among the most complex animal cell types known.
Plachetzki David C   +2 more
doaj   +1 more source

Hyperglycemia‐Induced Microglial CTSS Disrupts Blood‐Retinal Barrier Integrity via PAR2‐Dependent Downregulation of Endothelial MFSD2A

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Hyperglycemia induces retinal microglial activation and CTSS upregulation, disrupting microglia‐endothelial crosstalk via PAR2‐dependent MFSD2A suppression. Abnormal activation of microglia amplifies retinal inflammatory cascade, enhances transcytosis, compromises BRB integrity, and accelerates DR progression.
Chengye Xu   +8 more
wiley   +1 more source

Phototransduction and retinal degeneration in Drosophila [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2007
Drosophila visual transduction is the fastest known G-protein-coupled signaling cascade and has therefore served as a genetically tractable animal model for characterizing rapid responses to sensory stimulation. Mutations in over 30 genes have been identified, which affect activation, adaptation, or termination of the photoresponse.
Tao, Wang, Craig, Montell
openaire   +2 more sources

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 10, Page 2706-2711, October 2026.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan   +16 more
wiley   +1 more source

Multimodal targets of (‐)‐α‐thujone mediating avoidance behavior of a stored‐products pest, Tribolium castaneum, in response to irritant stimuli

open access: yesPest Management Science, Volume 82, Issue 10, Page 9592-9598, October 2026.
We identified four kinds of target molecules against (‐)‐α‐thujone associating avoidance behavior in Tribolium castaneum, indicating multimodality. Abstract BACKGROUND The reciprocal evolutionary processes among phytophagous insects and host plants involve host shift in the herbivorous insects in response to defense chemicals, such as plant‐derived ...
Kenji Shimomura   +4 more
wiley   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock in Drosophila melanogaster

open access: yesFrontiers in Molecular Neuroscience, 2018
Cryptochromes (CRYs) are a class of flavoproteins that sense blue light. In animals, CRYs are expressed in the eyes and in the clock neurons that control sleep/wake cycles and are implied in the generation and/or entrainment of circadian rhythmicity ...
Matthias Schlichting   +7 more
doaj   +1 more source

Control of the Nucleotide Cycle in Photoreceptor Cell Extracts by Retinal Degeneration Protein 3

open access: yesFrontiers in Molecular Neuroscience, 2018
Retinal degeneration protein 3 (RD3) is crucial for photoreceptor cell survival and linked to Leber Congenital Amaurosis type 12 (LCA12), a hereditary retinal disease in humans.
Hanna Wimberg   +2 more
doaj   +1 more source

Progress in phototransduction [PDF]

open access: yesBiophysics of Structure and Mechanism, 1983
STAVENGA, DG, DEGRIP, WJ, Grip, W.J. de
openaire   +3 more sources

ROS-GC interlocked Ca2+-sensor S100B protein signaling in cone photoreceptors: Review

open access: yesFrontiers in Molecular Neuroscience, 2014
Photoreceptor rod outer segment membrane guanylate cyclase (ROS-GC) is central to visual transduction; it generates cyclic GMP, the second messenger of the photon signal.
Rameshwar K Sharma   +3 more
doaj   +1 more source

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