Results 81 to 90 of about 14,467 (226)
A Calcium-Relay Mechanism in Vertebrate Phototransduction
, 2013 Calcium-signaling in cells requires a fine-tuned system of calcium-transport proteins involving ion channels, exchangers, and ion-pumps but also calcium-sensor proteins and their targets.
Karl Wilhelm Koch, DELL'ORCO, Daniele
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Glia, Volume 74, Issue 6, June 2026.Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar +2 more
wiley +1 more source
Modeling and simulation of phototransduction cascade in vertebrate rod photoreceptors
, 2019 Background The activation of phototransduction cascade in rod photoreceptors has been well studied in literature, but there is a lack of a mature kinetic model structure covering both the activation and inactivation processes.
Guofeng Pan, Jinglu Tan, Ya Guo
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A system-level, molecular evolutionary analysis of mammalian phototransduction [PDF]
, 2013 Background Visual perception is initiated in the photoreceptor cells of the retina via the phototransduction system. This system has shown marked evolution during mammalian divergence in such complex attributes as activation time and recovery time.
Montanucci, Ludovica +11 more
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Control of the Nucleotide Cycle in Photoreceptor Cell Extracts by Retinal Degeneration Protein 3
Frontiers in Molecular Neuroscience, 2018 Retinal degeneration protein 3 (RD3) is crucial for photoreceptor cell survival and linked to Leber Congenital Amaurosis type 12 (LCA12), a hereditary retinal disease in humans.
Hanna Wimberg +2 more
doaj +1 more source
Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
wiley +1 more source
Role of Guanylyl Cyclase Modulation in Mouse Cone Phototransduction
, 2011 A negative phototransduction feedback in rods and cones is critical for the timely termination of their light responses and for extending their function to a wide range of light intensities. The calcium feedback mechanisms that modulate phototransduction
Jeannie Chen +5 more
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Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy. [PDF]
, 2019 PurposeRecent evidence suggests that retinal photoreceptor cells have an important role in the pathogenesis of retinal microvascular lesions in diabetes.
Kern, Timothy +10 more
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ROS-GC interlocked Ca2+-sensor S100B protein signaling in cone photoreceptors: Review
Frontiers in Molecular Neuroscience, 2014 Photoreceptor rod outer segment membrane guanylate cyclase (ROS-GC) is central to visual transduction; it generates cyclic GMP, the second messenger of the photon signal.
Rameshwar K Sharma +3 more
doaj +1 more source