Results 161 to 170 of about 64,413 (204)

Hypoxia controls plasma membrane targeting of polarity proteins by dynamic turnover of PI4P and PI(4,5)P2. [PDF]

Elife, 2022
Lu J, Dong W, Hammond GR, Hong Y.
europepmc   +1 more source

Localization of the tubby domain, a PI(4,5)P2 biosensor, to E-Syt3-rich endoplasmic reticulum-plasma membrane junctions.

J Cell Sci, 2023
Thallmair V, Schultz L, Evers S, Jolie T, Goecke C, Leitner MG, Thallmair S, Oliver D.   +7 more
europepmc   +1 more source

The solute carrier SPNS2 recruits PI(4,5)P₂ to synergistically regulate transport of sphingosine-1-phosphate. [PDF]

Mol Cell, 2023
Tang H, Li H, Prakaash D, Pedebos C, Qiu X, Sauer DB, Khalid S, Duerr K, Robinson CV.   +8 more
europepmc   +1 more source

Enhanced channel activity by PI(4,5)P₂ ignites MLKL-related pathogenic processes. [PDF]

Cell Discov, 2022
Xia B, Qie J, Shen X, Wang S, Gao Z.
europepmc   +1 more source

Phosphatases-mediated control of phosphatidylinositol 4,5-biphosphate [PI(4,5)P2] in plant cells

, 2020
Les phosphoinositides sont des lipides membranaires anioniques peu abondants .Leurs concentrations relatives dans les feuillets cytosoliques de la membrane plasmique et de certaines membranes internes des cellules eucaryotes constituent des signatures moléculaires.
openaire   +1 more source

A cell-permeable fluorescent probe reveals temporally diverse PI(4,5)P2 dynamics evoked by distinct GPCR agonists in neurons. [PDF]

Chem Sci
Kundu R, Mondal S, Kapadia A, Banerjee AA, Kucherak OA, Klymchenko AS, Koushika SP, Venkatramani R, Vaidya VA, Datta A.   +9 more
europepmc   +1 more source

Membrane Curvature Generation through Asymmetric Desorption of Pi(4,5)P2 [PDF]

Biophysical Journal, 2019
Sankalp Shukla, Rui Jin, Tobias Baumgart
openaire   +1 more source

Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P₂ hydrolysis in the plasma membrane. [PDF]

J Biol Chem, 2023
Chen H, Lu C, Tan Y, Weber-Boyvat M, Zheng J, Xu M, Xiao J, Liu S, Tang Z, Lai C, Li M, Olkkonen VM, Yan D, Zhong W.   +13 more
europepmc   +1 more source

A phosphoinositide switch from PI(4,5)P₂ to PI4P triggers endocytosis by inducing dynamin-mediated fission in secretory cells. [PDF]

Sci Adv
Guo X, Wei L, Kundu N, Shin W, Chan CY, Han S, Mohseni A, Molakarimi M, Sun M, Wu XS, Jin Y, Hinshaw JE, Wu LG.   +12 more
europepmc   +1 more source

PI(4,5)P₂-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling. [PDF]

Sci Signal, 2022
Mahoney JP, Bruguera ES, Vasishtha M, Killingsworth LB, Kyaw S, Weis WI.   +5 more
europepmc   +1 more source