Similarity Between the Action of Pteridines and Tryptophan Metabolites on Lipid Metabolism
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH=7.4) containing 0.3% albumin, fatty acid mixture and glycerol. The addition of anthranilic acid (2.2 and
Rudzite Vera+3 more
doaj +1 more source
Interaction of solid organic acids with carbon nanotube field effect transistors [PDF]
A series of solid organic acids were used to p-dope carbon nanotubes. The extent of doping is shown to be dependent on the pKa value of the acids. Highly fluorinated carboxylic acids and sulfonic acids are very effective in shifting the threshold voltage and making carbon nanotube field effect transistors to be more p-type devices.
arxiv +1 more source
Background The mechanism behind the lowered postprandial insulin demand observed after rye bread intake compared to wheat bread is unknown. The aim of this study was to use the metabolomics approach to identify potential metabolites related to amino acid
Mykkänen Hannu+8 more
doaj +1 more source
Anomaly of the non-ergodicity parameter and crossover to white noise in the fast relaxation spectrum of a simple glass former [PDF]
We present quasi-elastic light scattering (LS) and dielectric (DS) spectra of the glass former alpha-picoline (13K < T < 320K). At high temperatures the evolution of the susceptibility minimum is well described by mode coupling theory (MCT) yielding a critical temperature T_c = 162K +- 5K.
arxiv +1 more source
Unraveling the degradation mechanism in FIrpic based Blue OLEDs: II. Trap and detect molecules at the interfaces [PDF]
The impact of organic light emitting diodes (OLEDs) in modern life is witnessed by their wide employment in full-color, energy-saving, flat panel displays and smart-screens; a bright future is likewise expected in the field of solid state lighting. Cyclometalated iridium complexes are the most used phosphorescent emitters in OLEDs due to their widely ...
arxiv +1 more source
Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv
Synthesis of 5-(substituted alkyl) picolinic acids. The dopamine beta-hydroxylase inhibitors. II.
5-Haloalkyl or 5-branched alkyl picolinic acids, dopamine β-hydroxylase inhibitor were synthesized by the various methods. 2-Methyl-5-ethynyl pyridine (III) reacted with alkyl dihalide followed by hydrogenation to give 2-methyl-5-haloalkyl pyridine.
K. Miyano, T. Sakasai, H. Hamano
semanticscholar +1 more source
Symmetry Scheme for Amino Acid Codons [PDF]
Group theoretical concepts are invoked in a specific model to explain how only twenty amino acids occur in nature out of a possible sixty four. The methods we use enable us to justify the occurrence of the recently discovered twenty first amino acid selenocysteine, and also enables us to predict the possible existence of two more, as yet undiscovered ...
arxiv +1 more source
An Alternative Mechanistic Paradigm for the Electrochemical C‐Terminal Decarboxylation of Peptides
Chemoselectivity in electrochemical oxidations is largely influenced by oxidation potential which represents a challenge for selectively oxidizing higher potential functional groups in complex substrates. Herein, a molecular binding strategy that selectively oxidizes the C‐terminal acid of a model peptide containing an electron‐rich tyrosine residue by
Adam J. Sowers+2 more
wiley +1 more source
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi+18 more
wiley +1 more source