Results 61 to 70 of about 519,483 (296)

Shell Neurons of the Master Circadian Clock Coordinate the Phase of Tissue Clocks Throughout the Brain and Body [PDF]

, 2015
Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined.
Baba, Kenkichi, Baker, Kimberly M., Bartness, Timothy J., Callif, Ben L., Castanon-Cervantes, Oscar, Davidson, Alec J., Ehlen, J. Christopher, Evans, Jennifer A., Kloehn, Ian, Leise, Tanya, Mitchell, Andrew S., Paul, Ketema N., Suen, Ting-Chung, Teubner, Brett J.W., Tosini, Gianluca   +14 more
core   +2 more sources

Mammalian Tolerance to Amino Acid Heterochirality

ChemBioChem, EarlyView.
Organisms preferentially use l‐amino acids (l‐AAs). However, de novo synthesized l‐AAs are in part converted to d‐AAs. The ribosome has a robust system to use l‐AAs for protein synthesis, whereas non‐ribosomal synthesis can also use d‐AAs. Furthermore, some AA residues can be post‐translationally isomerized through enzymatic or spontaneous processes ...
Sakiko Taniguchi, Kenichiro Adachi, Xuan Tran, Masataka Suzuki, Jumpei Sasabe   +4 more
wiley   +1 more source

Clinical and neurophysiological changes in patients with pineal region expansions [Kliničke i neurofiziološke značajke u bolesnika s ekspanzivnim tvorbama pinealne regije] [PDF]

, 2013
In the last 20 years neurological and neurosurgical follow up of our patients with pineal region expansions (118 patients) pointed to certain clinical and neurophysiological regularities.
Hajnšek, Sanja, Lupret, Velimir, Mrak, Goran, Nanković, Sibila, Paladino, Josip, Petelin Gadže, Željka   +5 more
core  

High concentrations of fluorescent nanoprobes delayed Oryzias melastigma embryo hatching by modulating respiratory and metabolic pathways

VIEW, EarlyView.
We investigated the developmental toxicity of a new graphene‐based fluorescent nanoprobe for tumor cell nucleus (GTTNs) using Oryzias melastigma embryos. The results confirmed that GTTNs have excellent biocompatibility for biomedical applications. Only the highest dose delayed hatching time.
Tianle Tang, Jinyan Chen, Jun Zhang, Pengcheng Pan, Jiahui Jiang, Chenyu Hu, Yuan He, Chenchen Li, Junfeng Zhang, Yanli Wang   +9 more
wiley   +1 more source

HISTOMORPHOGENESIS OF PINEAL GLAND IN GOAT FOETUSES [PDF]

Journal of Veterinary and Animal Sciences, 2011
Prenatal development of pineal gland in goat was studied using 52 goat foetuses ranging from 1.4cm CRL (24 days of gestation) to 41.5cm CRL (full term). Pineal gland developed during the seventh week as a conical evagination on the caudo-dorsal aspect of
K. M. Lucy, K. R. Harshan, J. J. Chungath, N. Ashok   +3 more
doaj  

Correction by peptide bioregulators of micro- and ultramicroscopic changes in the pineal gland caused by stress under light deprivation [PDF]

, 2015
It has been established, that immobilizing stress causes decreasing of light cell's amount in pineal gland, which are the main source of melatonin production like under usual lighting and like under light deprivation.
Bulyk, R.Ye., Lomakina, Yu.V.
core  

The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light

Nucleic Acids Research, 2014
Light constitutes a primary signal whereby endogenous circadian clocks are synchronized (‘entrained’) with the day/night cycle. The molecular mechanisms underlying this vital process are known to require gene activation, yet are incompletely understood ...
Z. Ben-Moshe, Shahar Alon, P. Mracek, Lior Faigenbloom, Adi Tovin, Gad D. Vatine, E. Eisenberg, N. Foulkes, Y. Gothilf   +8 more
semanticscholar   +1 more source

cba‐miR‐222‐3p involved in photoperiod‐induced apoptosis in testes of striped hamsters by targeting TRAF7

Integrative Zoology, EarlyView.
The cba‐miR‐222‐3p affects the MAPK signaling pathway by targeting TRAF7, thereby participating in the induction of apoptosis in the testes of striped hamsters under different photoperiods. Abstract The role of miRNAs in the regulation of seasonal reproduction in rodents, particularly in relation to photoperiod changes, is still poorly understood ...
Shuo WANG, Jinhui XU, Xingchen WANG, Mingdi WANG, Huiliang XUE, Ming WU, Chao FAN, Lei CHEN, Laixiang XU   +8 more
wiley   +1 more source

Functional Development of the Circadian Clock in the Zebrafish Pineal Gland

BioMed Research International, 2014
The zebrafish constitutes a powerful model organism with unique advantages for investigating the vertebrate circadian timing system and its regulation by light.
Z. Ben-Moshe, N. Foulkes, Y. Gothilf
semanticscholar   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos, Martin H. Teicher, Robert M. Post   +2 more
wiley   +1 more source