Results 31 to 40 of about 2,519,690 (191)
Titanium-based methylenations and their application to the synthesis of pipecolic acid derivatives [PDF]
, 2011 This thesis describes the use of titanium carbenoids for the synthesis of piperidinone alkaloids, in particular pipecolic acid derivatives, and the development of a new titanium-based strategy for the methylenation of carbonyl compounds including ...
Haahr, Adam
core +7 more sources
Molecules, 2023 Pipecolic acid (Pip) and its derivative hydroxypipecolic acids, such as (2S,3R)-3-hydroxypipecolic acid (cis-3-L-HyPip), are components of many natural and synthetic bioactive molecules. Fe(II)/α-ketoglutaric acid (Fe(II)/2-OG)-dependent dioxygenases can
Jiaojiao Guan +5 more
doaj +1 more source
Targeted Metabolomics Analysis Suggests That Tacrolimus Alters Protection against Oxidative Stress
Antioxidants, 2023 Tacrolimus (FK506) is an immunosuppressant that is experiencing a continuous rise in usage worldwide. The related side effects are known to be globally dose-dependent.
Marie Joncquel +14 more
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Effect of Pipecolic Acid Isomers on the Biogenesis of Actinomycins [PDF]
Antimicrobial Agents and Chemotherapy, 1974 Streptomyces antibioticus produces a family of actinomycin components which differ solely at the “imino acid” site of the molecule; however, new congeners of actinomycin are synthesized when cultures are supplemented with pipecolic acid (PA).
W S, May, J V, Formica
openaire +2 more sources
Crystal structure of (1R,4R)-tert-butyl 3-oxo-2-oxa-5-azabicyclo[2.2.2]octane-5-carboxylate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C11H17NO4, commonly known as N-tert-butoxycarbonyl-5-hydroxy-d-pipecolic acid lactone, the absolute configuration is (1R,4R) due to the enantiomeric purity of the starting material which remains unchanged during the course of the ...
Suvratha Krishnamurthy +4 more
doaj +1 more source
Frontiers in Plant Science, 2023 In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”.
Julián O. Miranda de la Torre +6 more
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Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy.
, 2005 Pyridoxine-dependent epilepsy, although described some decades ago, may still be an underdiagnosed disorder. We have recently described isolated pipecolic acid elevations in the plasma and/or CSF of three patients with pyridoxine-dependent epilepsy with ...
Plecko, B;Hikel, C;Korenke, GC;Schmitt, B;Baumgartner, M;Baumeister, F;Jakobs, C;Struys, E;Erwa, W;Stöckler-Ipsiroglu, S
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Antibiotics, 2023 Bacteria, filamentous fungi, and plants synthesize thousands of secondary metabolites with important biological and pharmacological activities. The biosynthesis of these metabolites is performed by networks of complex enzymes such as non-ribosomal ...
Paloma Liras, Juan Francisco Martín
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Advanced Science, EarlyView.AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source
The Xanthate Route to Amino Acids
CHIMIA, 2020 The degenerative xanthate addition transfer to alkenes allows the synthesis of a broad range of protected, and in some cases enantiopure, α, β, and γ-amino acids, including proline and pipecolic derivatives, as well as fluorinated congeners and β-lactams.
Samir Z. Zard
doaj +1 more source