Pyridoxine-Dependent Epilepsy and Pipecolic Acid
Pediatric Neurology Briefs, 2000 Two neonates with pyridoxine-dependent epilepsy and significant elevation of pipecolic acid in plasma and CSF are reported from the University Hospital Vienna, Austria.
J Gordon Millichap
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Pipecolic Acid, a Drought Stress Modulator, Boosts Chlorophyll Assimilation, Photosynthetic Performance, Redox Homeostasis, and Osmotic Adjustment of Drought-Affected Hordeum vulgare L. Seedlings [PDF]
PlantsWhile pipecolic acid (Pip) mediates morpho-physiological and molecular responses during biotic stress, its roles under drought remain an inexpressible mystery.
Nagihan Aktas +5 more
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Analysis of Dynamic Changes of Scallop (Patinopecten yessoensis) Adductor Muscle and Mantle by Non-Targeted Metabolomics [PDF]
FoodsA non-targeted metabolomics technique was employed to investigate the dynamic metabolite changes of scallop (Patinopecten yessoensis) adductor muscle (SAM) and scallop mantle (SM) during the early (E), middle (M), and late (L) harvest period from June to
Di Yu +12 more
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Agmatine and N-hydroxypipecolic acid synergistically enhance salt tolerance in wheat through antioxidant defense, proline metabolism, and photosynthetic protection [PDF]
Plant Signaling & BehaviorSalt stress severely limits wheat growth by disturbing photosynthesis, osmotic balance, and cellular redox homeostasis. This study evaluated whether agmatine and N-hydroxy pipecolic acid, applied alone or in combination, could improve wheat tolerance ...
Ghulam Murtaza +12 more
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Function of L-Pipecolic Acid as Compatible Solute in Corynebacterium glutamicum as Basis for Its Production Under Hyperosmolar Conditions [PDF]
Frontiers in Microbiology, 2019 Pipecolic acid or L-PA is a cyclic amino acid derived from L-lysine which has gained interest in the recent years within the pharmaceutical and chemical industries.
Fernando Pérez-García +2 more
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Oral pretreatment with Escherichia coli Nissle 1917 enhances the host's defense against influenza A virus infection [PDF]
mLifeInfluenza A viruses (IAVs) pose a significant threat to global health, causing annual epidemics and occasional pandemics with substantial morbidity and mortality.
Di Wang +7 more
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Microbial‐derived Exerkines preserve muscle size and function during disuse in aged mice in a sex‐dependent manner [PDF]
Physiological Reports, Volume 14, Issue 19, October 2026.Abstract Disuse‐induced muscle atrophy is a critical clinical challenge in older adults. Existing countermeasures have largely failed to preserve muscle size and function, underscoring the need for novel therapeutic strategies. We recently identified pipecolic acid and succinate (PAS) as microbial‐derived exerkines that prevent disuse‐induced atrophy ...
Jainil Daredia +5 more
wiley +2 more sources
Actinomycin Derivatives: Structural Diversification and Biological Activities [PDF]
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
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Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. [PDF]
J Med ChemMacrophage infectivity potentiator (MIP) proteins are present in many microbial pathogens, both of pro- and of eukaryotic origin. MIP proteins play important roles in microbial virulence, facilitating processes like host cell infection, pathogen ...
Pérez Carrillo VH +12 more
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A Simple and Highly Sensitive HPLC Method with Fluorescent Detection for Determination of Pipecolic Acid in Mouse Brain Areas [PDF]
, 2012 A simple and highly sensitive high-performance liquid chromatography method for the determination of pipecolic acid in mouse brain areas was developed. After homogenization of brain and pretreatment with o-phthalaldehyde, the pipecolic acid and (2S,3S)-3-
9000270162760 +23 more
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