Results 41 to 50 of about 43,723 (349)
Synthesis, and Antitumor Activity of Some N1-(Coumarin-7-yl) Amidrazones and Related Congeners
Molecules, 2011 A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines.
Mohammad S. Mustafa +4 more
doaj +1 more source
Piperazine-2,3,5,6-tetraone [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 The mol-ecule of the title compound, C(4)H(2)N(2)O(4), is located around an inversion center and the four O atoms are in the 2,3,5,6-positions of the piperazine ring. In the crystal, bifurcated N-H⋯O hydrogen bonds link the mol-ecules into a corrugated layer parallel to (101).
Yi-Min Jiang +4 more
openaire +3 more sources
Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives [PDF]
, 2014 Aminoindanes, piperazines, and pipradrol derivatives are novel psychoactive substances found in "Ecstasy" tablets as replacements for 3,4-methylenedioxymethamphetamine (MDMA) or substances sold as "ivory wave." The pharmacology of these MDMA- and ...
Hoener, Marius C. +4 more
core +1 more source
Research Progress on Detection of New Psychoactive Substance Piperazines in vivo
Fayixue ZazhiPiperazines are a class of new psychoactive substances with hallucinogenic effects that affect the central nervous system by affecting the level of monoamine neurotransmitters.
LIU Jin-ting +6 more
doaj +1 more source
Molecules, 2020 A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik +6 more
doaj +1 more source
Synthesis and pharmacological evaluation of several N-(2-nitrophenyl)piperazine derivatives [PDF]
Journal of the Serbian Chemical Society, 2007 Six newly synthesized heterocyclic (2-nitrophenyl)piperazines, with a specific structure of the heteroaryl group, whichmimics the catechol moiety of dopamine (benzimidazoles and substituted benzimidazoles), were evaluated for their binding affinity to ...
DEANA ANDRIC +6 more
doaj +3 more sources
Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives
Molecules, 2008 A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives 4a,b, 5a-c, 6, 7a-f, 8a-e and 9a,b have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, 1H ...
Safinaz Abbas +2 more
doaj +1 more source
Rigidity versus flexibility: is this an issue in S1 (sigma-1) receptor ligand affinity and activity? [PDF]
, 2016 A set of stereoisomeric 2,5-diazabicyclo[2.2.2]octanes 14 and 15 was prepared in a chiral-pool synthesis starting from (S)- or (R)-aspartate. The key step in the synthesis was a Dieckmann-analogous cyclization of (dioxopiperazinyl)acetates 8, which ...
B\uf6rgel, Frederik +10 more
core +1 more source
Chinese journal of chemistryA catalyst‐free and additive‐free ring‐opening reaction of polyfluoroalkyl peroxides, triethylenediamine (DABCO), and 1,2‐dichloroethane (DCE) has been developed for the defluorinative synthesis of structurally diverse piperazines featuring a fluoroenone
Yuan-Yuan Ren +6 more
semanticscholar +1 more source
A structural study of 2,4-dimethylaniline derivatives
Acta Crystallographica Section E: Crystallographic Communications, 2018 Crystallographic studies of nitrogen-containing small molecules aid in the elucidation of their structure–activity relationships and modes of aggregation.
Samuel C. Penner +2 more
doaj +1 more source