Results 41 to 50 of about 20,000 (189)
4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. [PDF]
PLoS ONE, 2017 Our ability to use ionizing radiation as an energy source, as a therapeutic agent, and, unfortunately, as a weapon, has evolved tremendously over the past 120 years, yet our tool box to handle the consequences of accidental and unwanted radiation ...
Ewa D Micewicz +17 more
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Piperazine-2,3,5,6-tetraone [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 The mol-ecule of the title compound, C(4)H(2)N(2)O(4), is located around an inversion center and the four O atoms are in the 2,3,5,6-positions of the piperazine ring. In the crystal, bifurcated N-H⋯O hydrogen bonds link the mol-ecules into a corrugated layer parallel to (101).
Jing-Jing Jia +4 more
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Piperazine Abuse and Psychosis: A Systematic Review of the Literature
Psychiatry InternationalBackground: Piperazines, synthetic compounds known for their stimulant and hallucinogenic effects, have gained prominence among novel psychoactive substances (NPS) and are frequently associated with adverse psychiatric outcomes, including psychosis ...
Alessio Mosca +9 more
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Synthesis and Antimicrobial Activity of Some Novel Substituted Piperazinyl-quinazolin-3(4H)-ones
E-Journal of Chemistry, 2008 Several substituted-quinazolin-3(4H)-ones were synthesized by condensation of 2-chloro-N-(4-oxo-substituted-quinazolin-3(4H)-yl)-acetamides with various substituted piperazines through single step reaction. Elemental analysis, IR, 1HNMR and mass spectral
N. M. Raghavendra +2 more
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Berichte der deutschen chemischen Gesellschaft, 1891 n ...
Schmidt, Albr, Wichmann, G.
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Designer drugs: aspectos analíticos e biológicos
Química Nova, 2012 In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão +7 more
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Complexation of Constrained Ligands Piperazine, N-substituted Piperazines, and Thiomorpholine
Australian Journal of Chemistry, 2009 Complexation of the symmetric cyclic diamine piperazine (1,4-diazacyclohexane) has been examined in dry dimethyl formamide by spectrophotometric titrations (with Cu2+, Ni2+) to define formation constants, and by stopped-flow kinetics to define the complexation rates and reaction pathway.
Clifford, Sarah E. +8 more
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Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted ...
Andrea Angeli +4 more
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Molecules, 2020 We reported a novel simplified synthetic procedure for the preparation of monosubstituted piperazine derivatives which can now be easily prepared in a one-pot-one-step way from a protonated piperazine with no need of introduction of a protecting group ...
Dana Němečková +4 more
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Molecules, 2015 Iridium-catalyzed asymmetric ring-opening of oxabenzonorbornadienes with N-substituted piperazines was described. The reaction afforded the corresponding ring-opening products in high yields and moderate enantioselectivities in the presence of 2.5 mol % [
Wen Yang, Renshi Luo, Dingqiao Yang
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