Results 101 to 110 of about 84,342 (322)

Crystal structure of the 1:2 adduct of bis(piperidinium) sulfate and 1,3-dimethylthiourea

Acta Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, 2C5H12N+·SO42−·2C3H8N2S, the C=S groups of the two independent 1,3-dimethylurea molecules and the sulfur atom of the anion lie on twofold axes. The packing is centred on bis(piperidinium) sulfate ribbons parallel to the c axis; the
Cindy Döring, Julian F. D. Lueck, Peter G. Jones   +2 more
doaj   +1 more source

Synthesis of dihydropyridine and piperidine derivatives via an unexpected reaction of pyridine with acetyl chloride [PDF]

, 2013
Acetyl chloride reacts with pyridine to give a mixture of N-acetyl-1,4- and 1,2-dihydropyridyl acetic acid (1a,b) after water quenching. The reactioninvolves the formation of a zwitterionic ketene enolate intermediate which results from deprotonation of
Mannu, Alberto, Spanu, Pietro, Ulgheri, Fausta   +2 more
core  

Photothermal Conversion Promotes Challenging SNAr for Facile C─N Bond Formation

Angewandte Chemie, EarlyView.
Photothermal conversion enables facile aromatic C─N bond formation via red light irradiation. A variety of inter‐ and intramolecular SNAr transformations are achieved under mild, schematically simple conditions. Additionally, a thermally promoted halogen exchange mechanism provides access to aryl bromides, chlorides, and fluorides – making this ...
Megan E. Matter, Rory C. Devin, Erin E. Stache   +2 more
wiley   +1 more source

Enantioselective synthesis of non-proteinogenic 2-arylallyl-α-amino acids via Pd/In catalytic cascades [PDF]

, 2006
An efficient synthesis of both R- and S-enantiomers of 2-arylallyl-α-amino acids via a diastereoselective Pd/In mediated catalytic allylation of chiral N-sulfinyl-α-imino esters is described.
Anwar, Anwar, Cleghorn, Cleghorn, Colin Kilner, Colin W.G. Fishwick, Cooper, Cooper, Cooper, Davis, Ellman, Ellman, Evans, Grigg, Grigg, Hodgson, Hohsaka, John Blacker, Kevin Bailey, Najera, Ronald Grigg, Shaun McCaffrey, Stewart Korn, Visuvanathar Sridharan   +23 more
core   +1 more source

Synthesis, crystal structure, Hirshfeld surface analysis, DFT, molecular docking and molecular dynamic simulation studies of (E)-2,6-bis(4-chlorophenyl)-3-methyl-4-(2-(2,4,6-trichlorophenyl)hydrazono)piperidine derivatives

, 2022
L. Athishu Anthony, D. Rajaraman, G. Sundararajan, M. Suresh, P. Nethaji, Jaganathan Ramakrishnan, P. Kumaradhas   +6 more
openalex   +2 more sources

Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes [PDF]

, 2012
Epitope-tagged active-site-directed probes are widely used to visualize the activity of deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small-molecule DUB inhibitors, and to isolate and identify DUBs by mass ...
Berlin, I., de Jong, A., El Atmioui, D., Merkx, R., Neefjes, J.J., Ovaa, H., Robson, C.N., Rodenko, B., Wijdeven, R.H.M., Yalçin, Z.   +9 more
core   +1 more source

Crystal structure of 2-chloro-1-(3-methyl-2,6-diphenylpiperidin-1-yl)ethanone

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C20H22ClNO, the piperidine ring has a twist-boat conformation. There is an intramolecular C—H...π interaction involving the two phenyl rings which are inclined to one another by 84.91 (7)°.
V. Shreevidhyaa Suressh, K. Prathebha, S. Abdul Basheer, S. Ponnuswamy, G. Usha   +4 more
doaj   +1 more source

Sonogashira/N-acyliminium ion aromatic π-cyclisation processes: access to tetra- and pentacyclic lactams [PDF]

, 2008
Application of the Sonogashira reaction of N-alkynylimides with 2-iodophenol or 2-iodo-N-tosylaniline affords 2-(N-alkylimino)-benzofurans and indoles in good yield.
Grigg, R., Sridharan, V., Sykes, D.A.
core   +1 more source

Stereoselective nucleophilic addition reactions to cyclic N-acyliminium ions using the indirect cation pool method: Elucidation of stereoselectivity by spectroscopic conformational analysis and DFT calculations

Beilstein Journal of Organic Chemistry, 2018
In this study, six-membered N-acyliminium ions were generated by the “indirect cation pool” method and reacted with several nucleophiles. These reactions afforded disubstituted piperidine derivatives with high diastereoselectivities and good to excellent
Koichi Mitsudo, Junya Yamamoto, Tomoya Akagi, Atsuhiro Yamashita, Masahiro Haisa, Kazuki Yoshioka, Hiroki Mandai, Koji Ueoka, Christian Hempel, Jun-ichi Yoshida, Seiji Suga   +10 more
doaj   +1 more source

Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential [PDF]

, 2012
A
Esposito, Fields, Guan, Henninge, Huff, King, Kohler, Kumar, Philp, Sosne, Thomas, Thomas, Thomas   +12 more
core   +2 more sources