Results 1 to 10 of about 46,002 (241)

Synthesis, Antimicrobial Activity and Cytotoxicity of Novel (Piperidin-4-yl)adamantane-1-carboxylate N-Substituted Derivatives [PDF]

Molecules
The cyclic adamantane framework possesses unique properties such as bulkiness, symmetry, and high lipophilicity. Research aimed at discovering new pharmaceutical agents within the adamantane series continues.
Kaldybay D. Praliyev, Gulmira S. Akhmetova, Ulzhalgas B. Issayeva, Samir A. Ross, Manas T. Omyrzakov, Ilya S. Korotetskiy, Ardak B. Jumagaziyeva, Aigul E. Malmakova, Tulegen M. Seilkhanov, Ubaidilla M. Datkhayev, Lyudmila N. Ivanova, Zhanar A. Iskakbayeva, Olzhas T. Seilkhanov, Natalya V. Zubenko   +13 more
doaj   +2 more sources

Enantioselective synthesis of chiral 2,3-cis-disubstituted piperidines and C1-substituted tetrahydroisoquinolines by asymmetric Cu-catalyzed cyclizative aminoboration [PDF]

Nature Communications
Chiral N-heterocycles such as piperidines and tetrahydroisoquinolines are privileged structural motifs in drug discovery and pharmaceutical industry.
Dazhuang Zhang, He Yang, Qinghai Zhou, Wenjun Tang   +3 more
doaj   +2 more sources

Search for Antiviral Preparations in Series of New Derivatives of N-Substituted Piperidines [PDF]

Molecules
Cyanohydrin synthesis, as the simplest preparative method for introducing a carboxyl group into a piperidine molecule, has been used to obtain potentially biologically active piperidinecarboxylic acids, which have alkyl and arylalkyl radicals at the ...
Gulmira S. Akhmetova, Ulzhalgas B. Issayeva, Kaldybay D. Praliyev, Ilya S. Korotetskiy, Tulegen M. Seilkhanov, Samir A. Ross, Manas T. Omyrzakov, Ubaidilla M. Datkhayev, Khaidar S. Tassibekov, Lyudmila N. Ivanova, Natalya V. Zubenko   +10 more
doaj   +2 more sources

PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines [PDF]

Beilstein Journal of Organic Chemistry, 2011
PEG-embedded potassium tribromide ([K+PEG]Br3−) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester.
Sanny Verma, Suman L. Jain, Bir Sain
doaj   +2 more sources

Ammonium piperidine-1-carbodithioate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
The title compound, NH(4) (+)·C(6)H(10)NS(2) (-), is composed of an ammonium cation and a piperidine-1-carbodithio-ate anion which exhibits positional disorder. The atoms of the ring have a structural disorder and they are divided into two sites, with occupancy factors of 0.584 and 0.426..
Ana C. Mafud, Maria T. P. Gambardella
openaire   +5 more sources

Experimental study of the pharmacological activity of new azaheterocycles derivatives: A literature review [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022
Diseases associated with the pathology of the cardiovascular system are one of the key causes of death all over the world. In particular, arrhythmia may entail the most severe complications, including unexpected death.
Malika Khaiitova, Aida Seitaliyeva, Elmira Satbayeva, Daniya Serdalieva, Talgat Nurgozhin   +4 more
doaj   +1 more source

Catalytic Enantioselective Synthesis of 3-Piperidines from Arylboronic Acids and Pyridine

Journal of the American Chemical Society, 2023
Piperidines are frequently found in natural products and are of importance to the pharmaceutical industry. A generally useful asymmetric route to enantiomerically enriched 3-substituted piperidines remains elusive.
Sourabh Mishra, Sedef Karabiyikoglu, S. Fletcher   +2 more
semanticscholar   +1 more source

Synthesis of piperidines and pyridine from furfural over a surface single-atom alloy Ru1CoNP catalyst

Nature Communications, 2023
The sustainable production of value-added N-heterocycles from available biomass allows to reduce the reliance on fossil resources and creates possibilities for economically and ecologically improved synthesis of fine and bulk chemicals.
Haifeng Qi, Yurou Li, Zhitong Zhou, Yueqiang Cao, Fei Liu, Weixiang Guan, Leilei Zhang, Xiaoyan Liu, Lin Li, Yang Su, K. Junge, Xuezhi Duan, Matthias Beller, Aiqin Wang, Tao Zhang   +14 more
semanticscholar   +1 more source

Synthesis and Characterization of Novel Methyl (3)5-(N-Boc-piperidinyl)-1H-pyrazole-4-carboxylates

Molecules, 2021
Series of methyl 3- and 5-(N-Boc-piperidinyl)-1H-pyrazole-4-carboxylates were developed and regioselectively synthesized as novel heterocyclic amino acids in their N-Boc protected ester form for achiral and chiral building blocks.
Gita Matulevičiūtė, Eglė Arbačiauskienė, Neringa Kleizienė, Vilija Kederienė, Greta Ragaitė, Miglė Dagilienė, Aurimas Bieliauskas, Vaida Milišiūnaitė, Frank A. Sløk, Algirdas Šačkus   +9 more
doaj   +1 more source

CeO2/CuO@N-GQDs@NH2 nanocomposite as a reusable and efficient catalyst for the synthesis of piperidines [PDF]

Nanochemistry Research, 2020
An efficient pseudo six-component synthesis of bis-spiropiperidinesis presented by one-pot condensation of formaldehyde, aromatic amine and dimedone or N,N-dimethyl-barbituric acid using CeO2/CuO@N-GQDs@NH2 nanocomposite at room temperature. The catalyst
Hossein Shahbazi-Alavi, Javad Safaei-Ghomi, Mozhgan Esfandiari   +2 more
doaj   +1 more source