Results 181 to 190 of about 24,641 (321)

Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1

, 2008
Wieslaw M. Kazmierski, Christopher Aquino, Brian A. Chauder, Felix Deanda, Robert G. Ferris, Deborah K. Jones-Hertzog, Terrence Kenakin, Cecilia S. Koble, Christian Watson, Pat Wheelan, Hanbiao Yang, Michael Youngman   +11 more
openalex   +1 more source

Sensorimotor Impairment and Incident Dementia in the US Medicare Beneficiaries

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Sensorimotor impairments, including sensory (vision and hearing) and motor (standing balance, gait, chair stands, grip strength) deficits, are prevalent in older adults and are associated with an increased risk of dementia. Understanding the individual and combined effects of these impairments on dementia risk may enhance early ...
Anis Davoudi, Ryan J. Dougherty, Amal A. Wanigatunga, Yuri Agrawal, Nicholas S. Reed, Joshua R. Ehrlich, Alden L. Gross, Jennifer A. Schrack   +7 more
wiley   +1 more source

[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9. [PDF]

Int J Oncol
Jin ML, Park SY, Kim YH, Park G, Lee SJ.
europepmc   +1 more source

II. SAR studies of pyridyl–piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists

, 2010
Yuefei Shao, G. Anilkumar, Carolyn DiIanni Carroll, Guizhen Dong, James W. Hall, Doug W. Hobbs, Yueheng Jiang, Chung‐Her Jenh, Seong Heon Kim, Joseph A. Kozlowski, Brian McGuinness, Stuart B. Rosenblum, Inna Schulman, Neng‐Yang Shih, Youheng Shu, Michael Wong, Wensheng Yu, Lisa Guise Zawacki, Qingbei Zeng   +18 more
openalex   +1 more source

RrMYB2 Regulates Drought Stress via RrJMJ12‐Dependent Epigenetic Modification in Rosa rugosa

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rosa rugosa (R. rugosa), an economically important crop valued for its fragrance and medicinal properties, is highly susceptible to drought stress under open‐field cultivation. However, the molecular mechanisms underlying its drought response remain largely unexplored.
Mengjuan Bai, Yating Yang, Yunfeng Gao, Mengmeng Xu, Qianxiang Zhang, Shuo Liu, Jun Lu, Jianwen Wang, Changquan Wang, Liguo Feng   +9 more
wiley   +1 more source

Transaminase-Triggered Cascades for the Synthesis and Dynamic Kinetic Resolution of Chiral N-Heterocycles. [PDF]

Angew Chem Int Ed Engl
O'Connell A, Haarr MB, Ryan J, Xu X, Martin A, Smith SN, Elghobashi-Meinhardt N, Fleming P, Maciá B, Caprio V, O'Reilly E.   +10 more
europepmc   +1 more source

Potent and Selective Ligands for the Dopamine Transporter (DAT):  Structure−Activity Relationship Studies of Novel 4-[2-(Diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine Analogues

, 1998
Aloke K. Dutta, Lori L. Coffey, Maarten E. A. Reith   +2 more
openalex   +1 more source

Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal, Raphael Hitti, William D. Lubell   +2 more
wiley   +1 more source

Electronic Activation Enables the Borylation of Alkyl C-H Bonds in Saturated Nitrogen Heterocycles. [PDF]

J Am Chem Soc
D'Angelo KA, Zheng R, Yu IF, Tang MJ, La C, Wetterer RT, Hartwig JF.   +6 more
europepmc   +1 more source

Diphenylsulfone muscarinic antagonists: piperidine derivatives with high m2 selectivity and improved potency

, 2000
William Billard, Herbert Binch, Kristen Bratzler, Lian-Yong Chen, Gordon Crosby, Ruth A. Duffy, Sundeep Dugar, Jean E. Lachowicz, Robert McQuade, Pradeep Pushpavanam, Vilma Ruperto, Lisa A. Taylor, John W. Clader   +12 more
openalex   +1 more source