Results 51 to 60 of about 191,349 (283)

Alantolactone induces platelet apoptosis by activating the Akt pathway

open access: yesPlatelets, 2023
Alantolactone (ALT), a sesquiterpene lactone compound isolated from Inula helenium L., has recently attracted much attention for its anti-tumor properties.
Yueyue Sun   +7 more
doaj   +1 more source

Protein Kinase A(PKA)-Restrictcive and PKA-Permissive Phases of Oocyte Maturation [PDF]

open access: yesCell Cycle, 2005
Substantial evidence has indicated that cAMP-dependent protein kinase (protein kinase A or PKA) plays a critical role in maintaining meiotic prophase arrest in vertebrate oocytes. However, PKA activity dynamic and its physiological substrate profile during oocyte maturation remain poorly defined.
Jing, Wang   +2 more
openaire   +2 more sources

Output-files-pka-COOH

open access: yes, 2016
All the output files for the calculations of pKa values.
Annia Galano (3224100)
core   +1 more source

Characterization of a PKA-like kinase from Trypanosoma brucei [PDF]

open access: yes, 2005
The protozoan parasite Trypanosoma brucei causes human sleeping sickness and Nagana in domestic animals and depends on the tsetse fly for dissemination. The complex T.
Kramer, Susanne
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA

open access: yesMicrobial Cell, 2020
A major signal transduction pathway regulating cell growth and many associated physiological properties as a function of nutrient availability in the yeast Saccharomyces cerevisiae is the protein kinase A (PKA) pathway.
Griet Van Zeebroeck   +4 more
doaj   +1 more source

Comparison of pKa values for oxy-enzymase derivatives derived from 3-acetyl and 4-acetyl-3 serotonin by using glass pole [PDF]

open access: yesمجلة التربية والعلم, 2014
The study includes the preparation of four syn and anti oximes derived from mother ketones, namely 3-acetyl and 4-acetyl pyridine by standard method. The structures of these oximes were confirmed by using UV and IR spectra, melting points and specific ...
Adel Azzoz, rawaa Suliaman
doaj   +1 more source

Additional file 3 of Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway

open access: yes, 2022
Additional file 3: Figure S3. Agomelatine has no effects on behavioral and 5-HT2C signaling pathway in rats. (A) Agameratine had no effect on percent of sucrose consumption with normal rats in the SPT and (B) didn’t increased immobility time in normal ...
Shuhan Li (5684267)   +10 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Protein kinase A (PKA) phosphorylation of Shp2 inhibits its phosphatase activity and modulates ligand specificity. [PDF]

open access: yes, 2015
Pathological cardiac hypertrophy (an increase in cardiac mass resulting from stress-induced cardiac myocyte growth) is a major factor underlying heart failure.
O'Bryan, JP   +5 more
core  

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