Results 81 to 90 of about 5,277,200 (190)
Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
eLife, 2018 Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior ...
Ilya Chuykin +2 more
doaj +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
MedComm, Volume 7, Issue 9, September 2026.The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Planar cell polarity: global inputs establishing cellular asymmetry
, 2018 Many tissues develop coordinated patterns of cell polarity that align with respect to the tissue axes. This phenomenon refers to planar cell polarity (PCP) and is controlled by multiple conserved PCP modules.
Devenport, Danelle, Aw, Wen Yih
core +1 more source
Polarity Establishment and Maintenance in Ascidian Notochord
Frontiers in Cell and Developmental Biology, 2020 Cell and tissue polarity due to the extracellular signaling and intracellular gene cascades, in turn, signals the directed cell behaviors and asymmetric tissue architectures that play a crucial role in organogenesis and embryogenesis.
Hongzhe Peng +4 more
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Kermit interacts with Gαo, Vang, and motor proteins in Drosophila planar cell polarity. [PDF]
PLoS ONE, 2013 In addition to the ubiquitous apical-basal polarity, epithelial cells are often polarized within the plane of the tissue--the phenomenon known as planar cell polarity (PCP).
Chen Lin, Vladimir L Katanaev
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Actinomycin Derivatives: Structural Diversification and Biological Activities
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length. [PDF]
PLoS Genetics, 2009 Epithelial tubes are the functional units of many organs, and proper tube geometry is crucial for organ function. Here, we characterize serrano (sano), a novel cytoplasmic protein that is apically enriched in several tube-forming epithelia in Drosophila,
SeYeon Chung +5 more
doaj +1 more source
BODIPY‐based J‐aggregates: From supramolecular chemistry to NIR bioimaging and phototherapies
Bulletin of the Korean Chemical Society, Volume 47, Issue 8, Page 951-982, August 2026.BODIPY dyes form ordered J‐aggregates through controlled supramolecular self‐assembly, producing narrow, red‐shifted absorption bands with small Stokes shifts. This review highlights design strategies governing J‐aggregation, structure–property relationships, and applications in sensing, bioimaging, and phototherapy, guiding functional BODIPY‐based ...
Pooja Sharma +2 more
wiley +1 more source
Mitotic Control of Planar Cell Polarity by Polo-like Kinase 1 [PDF]
, 2015 SummaryDuring cell division, polarized epithelial cells employ mechanisms to preserve cell polarity and tissue integrity. In dividing cells of the mammalian skin, planar cell polarity (PCP) is maintained through the bulk internalization, equal ...
Perlman, David H. +5 more
core +1 more source
Biology Open, 2012 Summary In addition to their ubiquitous apical-basal polarity, many epithelia are also polarized along an orthogonal axis, a phenomenon termed planar cell polarity (PCP).
Ivana Mirkovic +2 more
doaj +1 more source