Results 61 to 70 of about 5,277,200 (190)

Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity

Cell Reports, 2020
Summary: Cell polarity is essential for the architecture and function of numerous epithelial tissues. Here, we show that apical restriction of planar cell polarity (PCP) components is necessary for the maintenance of epithelial integrity.
Lydie Flasse, Siham Yennek, Cédric Cortijo, Irene Seijo Barandiaran, Marine R.-C. Kraus, Anne Grapin-Botton   +5 more
doaj   +1 more source

Is a persistent global bias necessary for the establishment of planar cell polarity? [PDF]

PLoS ONE, 2013
Planar cell polarity (PCP)--the coordinated polarisation of a whole field of cells within the plane of a tissue-relies on the interaction of three modules: a global module that couples individual cellular polarity to the tissue axis, a local module that ...
Sabine Fischer, Paul Houston, Nicholas A M Monk, Markus R Owen   +3 more
doaj   +1 more source

A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled

bioRxiv, 2022
Epithelial tissues can be polarized along two axes, in addition to apical-basal polarity they are often also polarized within the plane of the epithelium, known as planar cell polarity (PCP).
Ashley C. Humphries, Claudia Molina-Pelayo, Parijat Sil, C. C. Hazelett, D. Devenport, M. Mlodzik   +5 more
semanticscholar   +1 more source

Diminished Expression of Fat and Dachsous PCP Proteins Impaired Centriole Planar Polarization in Drosophila

Frontiers in Genetics, 2019
Proper ciliary basal body positioning within a cell is key for cilia functioning. Centriole and basal body positioning depends on signaling pathways such as the planar cell polarity pathway (PCP) governed by Frizzled (Fz-PCP).
Sergio Garrido-Jimenez, Angel-Carlos Roman, Jose Maria Carvajal-Gonzalez   +2 more
doaj   +1 more source

Cytoplasmic Dynein Functions in Planar Polarization of Basal Bodies within Ciliated Cells

iScience, 2020
Summary: Despite common consensus about the importance of planar cell polarity (PCP) proteins in tissue orientation, little is known about the mechanisms used by PCP proteins to promote planar polarization of cytoskeletons within individual cells.
Maki Takagishi, Nobutoshi Esaki, Kunihiko Takahashi, Masahide Takahashi   +3 more
doaj   +1 more source

Planar cell polarity protein Celsr1 regulates endothelial adherens junctionsand directed cell rearrangements during lymphatic valve morphogenesis. [PDF]

, 2013
Planar cell polarity (PCP) signaling controls tissue morphogenesis by coordinating collective cell behaviours. Here we show a critical role for the core PCP proteins Celsr1 and Vangl2 in the complex morphogenetic process of intraluminal valve formation ...
Devenport, Danelle, Weston, Anne, Taddei, Andrea, Makinen, Taija, Mäkinen, Taija,, Davenport, Danelle, Fuchs, Elaine, Tatin, Florence, Tissir, Fadel   +8 more
core   +1 more source

Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling

Nature Communications, 2016
Planar cell polarity (PCP) contributes to cellular orientation during development but how this is regulated in Drosophilais unclear. Here, the authors identify Frizzled-PCP signalling as regulating polarised centriole positioning in the wing disc.
Jose Maria Carvajal-Gonzalez, Angel-Carlos Roman, Marek Mlodzik   +2 more
doaj   +1 more source

Planar cell polarity protein Celsr2 maintains structural and functional integrity of adult cortical synapses.

Progress in neurobiology, 2022
A few developmental genes remain persistently expressed in the adult stage, whilst their potential functions in the mature brain remain underappreciated. Here, we report the unexpected importance of Celsr2, a core Planar cell polarity (PCP) component, in
Cunzhen Li, Ji-An Wei, Di Wang, Zhihua Luo, C. Pang, Kai Chen, Juan Duan, Bailing Chen, Libing Zhou, F. Tissir, Lei Shi, K. So, Li Zhang, Y. Qu   +13 more
semanticscholar   +1 more source

Temperature and Growth Selection Effects on Proliferation, Differentiation, and Adipogenic Potential of Turkey Myogenic Satellite Cells Through Frizzled-7-Mediated Wnt Planar Cell Polarity Pathway

Frontiers in Physiology, 2022
Satellite cells (SCs) are a heterogeneous population of multipotential stem cells. During the first week after hatch, satellite cell function and fate are sensitive to temperature.
Jiahui Xu, G. Strasburg, K. Reed, S. Velleman   +3 more
semanticscholar   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source