Comparing plasma and faecal measures of steroid hormones in Adelie penguins Pygoscelis adeliae [PDF]
Physiological measurements of both stress and sex hormones are often used to estimate the consequences of natural or human-induced change in ecological studies of various animals.
Möstl, E. +39 more
core +1 more source
Impact of cytochrome P450 2D6 function on the chiral blood plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its phase I and II metabolites in humans [PDF]
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) metabolism is known to be stereoselective, with preference for S-stereoisomers. Its major metabolic step involves CYP2D6-catalyzed demethylenation to 3,4-dihydroxymethamphetamine (DHMA), followed by ...
Tingelhoff, Eva H. +33 more
core +1 more source
Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites
Background: Enteroendocrine cells are essential for the regulation of glucose metabolism, but it is unknown whether they are associated with clinical features of metabolic syndrome (MetS) and fasting plasma metabolites.
Annieke C G van Baar +8 more
doaj +1 more source
Pharmacokinetics of torasemide and its metabolites in end-stage renal disease [PDF]
The pharmacokinetics of torasemide, a new loop diuretic, as well as its active metabolites M1 and M3, and its inactive main metabolite, M5, were studied in 12 patients with end-stage renal failure during single i.v.
Schwab, A. +5 more
core +1 more source
Art. 573, 12 S.Administration of pivalate has been demonstrated to be suitable for the induction of secondary carnitine deficiency (CD) in pigs, as model objects for humans.
Ringseis, R. +4 more
core +1 more source
Decreasing resistance in the maternal uterine and peripheral arterial system is apparently unrelated to plasma and urinary levels of nitrite/nitrate and cyclic-guanosinmonophosohate during the course of normal pregnancies [PDF]
Aims: The aim of the presented study was to clarify the relationship between the pulsatility index of the uterine arteries and the maternal cubital artery and peripheral concentrations of the metabolites of nitric oxide (NO) and its second messenger ...
Schiessl, B. +5 more
core +1 more source
Heatmap correlation between plasma metabolites in total population.
Heatmap correlation between plasma metabolites in total population.
Moein Yoosefi (6208442) +12 more
core +1 more source
Background: A growing body of evidence has found links between endocrine disruptor phthalates and male reproductive disorders, but the mechanisms underlying these relationships are poorly known.
Yi-Xin Wang +12 more
doaj +1 more source
Piperaquine and Metabolites - Bioanalysis and Pharmacokinetics [PDF]
Antimalarial piperaquine (PQ) is currently used as a partner drug with dihydroartemisinin (DHA), exhibiting high cure rates (>95%) for P. falciparum.
Aziz, Mohd Yusmaidie +6 more
core +1 more source
Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance
Summary Objective Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope‐based hyperinsulinemic ...
Annick V. Hartstra +10 more
doaj +1 more source

