Results 41 to 50 of about 2,029,441 (265)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Genetically predicted plasma metabolites mediate the causal relationship between gut microbiota and osteosarcoma

Scientific Reports
Previous research has demonstrated a close connection between the development of osteosarcoma (OS) and variations in the abundance of specific gut microbiota (GM). Generally speaking, GM play a role in human health mostly through metabolites.
Xiuyu Qin, Zhuming Fan, Shaopeng Qiao, Jian Li, Jia Lv   +4 more
doaj   +1 more source

Metabolites identified in bull seminal plasma by GC-MS.

, 2018
Metabolites identified in bull seminal plasma by GC-MS.
Arlindo Alencar Moura (5081870), Ana Luiza Cazaux Velho (5081867), Erika Menezes (5081876), Einko Topper (5081864), Thu Dinh (5081873), Abdullah Kaya (44754), Erdogan Memili (44756)   +6 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Determinations of NO metabolites in plasma and RBC.

, 2019
Determinations of NO metabolites in plasma and RBC.
Kulwant S. Aulak (2375956), Alfred Hausladen (7329929), Stephen C. Rogers (6112082), Adriano R. Tonelli (4804245), Benjamin Gaston (363273), Raed A. Dweik (7329935), Charlie J. Casa (7329932), Mostafa K. Ahmed (7329926), Batool Abuhalimeh (4804242), Allan Doctor (364021), David Timm (2739016)   +10 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mangiferin effects on plasma metabolites in obese rats.

, 2017
Mangiferin effects on plasma metabolites in obese rats.
José-Luis L. Rivero (3808516), Ana I. Raya (3808522), Escolástico Aguilera–Tejero (3808513), Julio M. Martínez-Moreno (172835), Luz M. Acevedo (3808519)   +4 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source