Results 61 to 70 of about 64,860 (240)
Nutrition, diet and immunosenescence [PDF]
Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease.
Agrawal +217 more
core +1 more source
Plasmacytoid dendritic cells in the eye
Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct from classical dendritic cells. pDCs are generated in the bone marrow and following development, they typically home to secondary lymphoid tissues. While peripheral tissues are generally devoid of pDCs during steady state, few tissues, including the lung, kidney ...
Arsia Jamali +6 more
openaire +3 more sources
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy that usually occurs in elderly individuals and manifests with skin lesions followed by involvement of the lymph nodes, bone marrow, and peripheral blood.
Chien-yio Lin +3 more
doaj +1 more source
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
core +2 more sources
Another Heritage for Plasmacytoid Dendritic Cells [PDF]
Plasmacytoid dendritic cell (pDC) development has been linked to that of conventional dendritic cells via a common dendritic cell precursor (CDP). In this issue of Immunity, Onai et al. (2013) outline a parallel but more effective pathway to pDCs that proceeds via a novel CDP-like precursor.
Shortman, Ken, Sathe, Priyanka
openaire +2 more sources
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
Immunodetection of myeloid and plasmacytoid dendritic cells in mammary carcinomas of female dogs
: Dendritic cells have attracted great interest from researchers as they may be used as targets of tumor immune evasion mechanisms. The main objective of this study was to evaluate the relationship between the dendritic cells (DCs) subpopulation in ...
Mayara C. Rosolem +7 more
doaj +1 more source
Subsets of migrating intestinal dendritic cells [PDF]
Dendritic cells (DCs) in the intestine are heterogeneous. Phenotypically different populations of conventional DCs have been identified in the intestinal lamina propria, Peyer's patches, and in the draining mesenteric lymph nodes, to which these DCs ...
Allan +68 more
core +1 more source
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source

