Results 11 to 20 of about 5,427 (205)

Involvement of plasmalogens in post-natal retinal vascular development. [PDF]

PLoS ONE, 2014
Proper development of retinal blood vessels is essential to ensure sufficient oxygen and nutrient supplies to the retina. It was shown that polyunsaturated fatty acids (PUFAs) could modulate factors involved in tissue vascularization.
Sarah Saab, Bénédicte Buteau, Laurent Leclère, Alain M Bron, Catherine P Creuzot-Garcher, Lionel Bretillon, Niyazi Acar   +6 more
doaj   +2 more sources

Dietary plasmalogen increases erythrocyte membrane plasmalogen in rats [PDF]

Lipids in Health and Disease, 2012
Background Many disorders with plasmalogen deficiency have been reported. Replenishment or replacement of tissue plasmalogens of these disorders would be beneficial to the patients with these disorders, but effects of dietary plasmalogen on mammals have ...
Mawatari Shiro, Katafuchi Toshihiko, Miake Kiyotaka, Fujino Takehiko   +3 more
doaj   +3 more sources

Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer’s Disease

The Scientific World Journal, 2012
Lipids play an important role as risk or protective factors in Alzheimer’s disease (AD). Previously it has been shown that plasmalogens, the major brain phospholipids, are altered in AD.
Tatjana L. Rothhaar, Sven Grösgen, Viola J. Haupenthal, Verena K. Burg, Benjamin Hundsdörfer, Janine Mett, Matthias Riemenschneider, Heike S. Grimm, Tobias Hartmann, Marcus O. W. Grimm   +9 more
doaj   +2 more sources

Plasmalogens and Chronic Inflammatory Diseases [PDF]

Frontiers in Physiology, 2021
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating a variety of biological processes. Lately, a subclass of glycerophospholipids, namely plasmalogens, has received increased attention due to their association ...
José Carlos Bozelli, Sayed Azher, Richard M. Epand   +2 more
doaj   +3 more sources

Plasmalogens and Alzheimer’s disease: a review [PDF]

Lipids in Health and Disease, 2019
Growing evidence suggests that ethanolamine plasmalogens (PlsEtns), a subtype of phospholipids, have a close association with Alzheimer's disease (AD). Decreased levels of PlsEtns have been commonly found in AD patients, and were correlated with cognition deficit and severity of disease.
Xiao Q. Su, Junming Wang, Andrew J. Sinclair   +2 more
core   +7 more sources

On the synthesis of plasmalogens [PDF]

Chemistry and Physics of Lipids, 1967
The chemical synthesis is described of (rac)-trans-1-(n-hexadec-1′-enyloxy)-2-oleoylglycerol-3-phosphorylcholine (plasmalogen). This synthesis made use of a specific degradation of (rac)-trans-1-(n-hexadec-1′-enyloxy)-2,3-dioleoyl glycerol with pancreatic lipase (EC 3.1.1.3).
Slotboom, A.J., Haas, Gerard H. de, Deenen, L.L.M. van   +2 more
openaire   +3 more sources

Ethanolamine plasmalogens increase luteinising hormone pulsatility and are associated with GPR61 expression in bovine gonadotrophin-releasing hormone neurons. [PDF]

J Neuroendocrinol
Ethanolamine plasmalogens increased LH pulse frequency. GPR61 was expressed in GnRH neurons and gonadotrophs, suggesting a role in neuroendocrine regulation. Ethanolamine plasmalogens (EPls), but not choline plasmalogens (CPls), may act via GPR61 expressed in GnRH neurons in the preoptic area and in anterior pituitary gonadotrophs.
Kadokawa H, Kubo T, Kobayashi K, Wanjiru DK, Niyonzima YB.   +4 more
europepmc   +2 more sources

Plasmalogen Replacement Therapy [PDF]

Membranes, 2021
Plasmalogens, a subclass of glycerophospholipids containing a vinyl-ether bond, are one of the major components of biological membranes. Changes in plasmalogen content and molecular species have been reported in a variety of pathological conditions ranging from inherited to metabolic and degenerative diseases.
José Carlos Bozelli, Richard M. Epand
openaire   +3 more sources

Fatty Acid Signatures as Nutritional Indices: Molecular Gateways to Health, Aging, and Functional Food Innovation. [PDF]

Food Sci Nutr
Systems framework linking dietary fatty acids with the functional lipidome, health, and precision nutrition. Dietary fatty acids from plant‐based, marine, and animal sources undergo absorption, endogenous desaturation and elongation, oxidation, and tissue‐specific incorporation and remodeling, generating individualized FA signatures.
Bhuiyan MNI, Reza MS, Mim F.
europepmc   +2 more sources

Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia. [PDF]

Mol Nutr Food Res
Peroxisomes are emerging as key regulators of lipid metabolism in leukemia. Enhanced metabolism of very‐long‐chain fatty acids (VLCFAs) supports leukemia cell survival, redox homeostasis, and therapeutic resistance. Pharmacologic disruption of peroxisomal fatty acid oxidation causes VLCFA accumulation, oxidative stress, and mitochondrial dysfunction ...
Parfenova EN, Spagnuolo PA.
europepmc   +2 more sources