Results 21 to 30 of about 5,427 (205)

Tricky Isomers—The Evolution of Analytical Strategies to Characterize Plasmalogens and Plasmanyl Ether Lipids

Frontiers in Cell and Developmental Biology, 2022
Typically, glycerophospholipids are represented with two esterified fatty acids. However, by up to 20%, a significant proportion of this lipid class carries an ether-linked fatty alcohol side chain at the sn-1 position, generally referred to as ether ...
Jakob Koch, Katrin Watschinger, Ernst R. Werner, Markus A. Keller   +3 more
doaj   +1 more source

Regulation of plasmalogen metabolism and traffic in mammals: The fog begins to lift

Frontiers in Cell and Developmental Biology, 2022
Due to their unique chemical structure, plasmalogens do not only exhibit distinct biophysical and biochemical features, but require specialized pathways of biosynthesis and metabolization.
Fabian Dorninger, Ernst R. Werner, Johannes Berger, Katrin Watschinger   +3 more
doaj   +1 more source

Lymphatic Absorption of Microbial Plasmalogens in Rats

Frontiers in Cell and Developmental Biology, 2022
Plasmalogens, functional glycerophospholipids with biological roles in the human body, are associated with various diseases. Although a variety of saturated and/or unsaturated fatty acids in plasmalogens are presumed to have different functions in the ...
Nana Sato, Aki Kanehama, Akiko Kashiwagi, Miwa Yamada, Miwa Yamada, Megumi Nishimukai, Megumi Nishimukai   +6 more
doaj   +1 more source

Plasmalogens and Photooxidative Stress Signaling in Myxobacteria, and How it Unmasked CarF/TMEM189 as the Δ1′-Desaturase PEDS1 for Human Plasmalogen Biosynthesis

Frontiers in Cell and Developmental Biology, 2022
Plasmalogens are glycerophospholipids with a hallmark sn-1 vinyl ether bond that endows them with unique physical-chemical properties. They have proposed biological roles in membrane organization, fluidity, signaling, and antioxidative functions, and ...
S. Padmanabhan, Antonio J. Monera-Girona, Elena Pajares-Martínez, Eva Bastida-Martínez, Irene del Rey Navalón, Ricardo Pérez-Castaño, María Luisa Galbis-Martínez, Marta Fontes, Montserrat Elías-Arnanz   +8 more
doaj   +1 more source

Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidemia and inflammation

Journal of Lipid Research, 2021
Plasmalogens are membrane glycerophospholipids with diverse biological functions. Reduced plasmalogen levels have been observed in metabolic diseases; hence, increasing their levels might be beneficial in ameliorating these conditions.
Sudip Paul, Adam Alexander T. Smith, Kevin Culham, Kevin A. Gunawan, Jacqueline M. Weir, Michelle A. Cinel, Kaushala S. Jayawardana, Natalie A. Mellett, Man K.S. Lee, Andrew J. Murphy, Graeme I. Lancaster, Paul J. Nestel, Bronwyn A. Kingwell, Peter J. Meikle   +13 more
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Plasmalogen composition of Anaeroplasma [PDF]

Journal of Bacteriology, 1975
The polar lipids of Anaeroplasma contained 33.1 percent alk-1'-enyl glyceryl ether (plasmalogen) form. Phosphatidylglycerol was the major polar lipid (55.2 percent) and contained nearly all of the plasmalogen. The alk-1'-enyl glyceryl ether form accounted for 58.3 percent of the phosphatidylglycerol.
T A, Langworthy, W R, Mayberry, P F, Smith, I M, Robinson   +3 more
openaire   +2 more sources

The Changes in Plasmalogens: Chemical Diversity and Nutritional Implications-A Narrative Review. [PDF]

Nutrients
Plasmalogens, as natural dietary lipids, are a unique class of glycerophospholipids with distinct structural and functional properties. They are unstable due to the vinyl ether linkage and the unsaturated fatty chains.
Chen Z, Dong C, Chen L, Song M, Zhou X, Lv D, Li Q.   +6 more
europepmc   +2 more sources

Plasmalogen homeostasis – regulation of plasmalogen biosynthesis and its physiological consequence in mammals [PDF]

FEBS Letters, 2017
Plasmalogens, mostly ethanolamine‐containing alkenyl ether phospholipids, are a major subclass of glycerophospholipids. Plasmalogen synthesis is initiated in peroxisomes and completed in the endoplasmic reticulum. The absence of plasmalogens in several organs of peroxisome biogenesis‐defective patients suggests that the de novo synthesis of ...
Masanori, Honsho, Yukio, Fujiki
openaire   +2 more sources

The anaerobic biosynthesis of plasmalogens [PDF]

FEBS Letters, 2017
The biosynthesis of plasmalogens in anaerobic bacteria differs fundamentally from that in animal cells. Firstly, the formation of the alk‐1′‐enyl ether bond in animal cells is oxygen dependent. Secondly, the first step in plasmalogen formation in animal cells is an acylation of dihydroxyacetone phosphate, which has been ruled out as a precursor in ...
openaire   +2 more sources

Plasmalogens, the Vinyl Ether-Linked Glycerophospholipids, Enhance Learning and Memory by Regulating Brain-Derived Neurotrophic Factor

Frontiers in Cell and Developmental Biology, 2022
Plasmalogens (Pls), a kind of glycerophospholipids, have shown potent biological effects but their role in hippocampus-dependent memory remained mostly elusive.
Md. Shamim Hossain, Shiro Mawatari, Takehiko Fujino   +2 more
doaj   +1 more source