Results 51 to 60 of about 5,427 (205)
Functions and biosynthesis of plasmalogens in health and disease
, 2004 Plasmalogens (1-O-alk-1'-enyl-2-acyl glycerophospholipids) constitute a special class of phospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position.
Waterham, H. R. +2 more
core +1 more source
Energetic dysregulations in psychotic disorders: Targets for new therapeutics
The FEBS Journal, EarlyView.The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson +10 more
wiley +1 more source
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Human and great ape red blood cells differ in plasmalogen levels and composition
Lipids in Health and Disease, 2011 Background Plasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as ...
Ely John J +9 more
doaj +1 more source
Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration
Journal of Lipid Research, 2021 Vascular disease contributes to neurodegeneration, which is associated with decreased blood pressure in older humans. Plasmalogens, ether phospholipids produced by peroxisomes, are decreased in Alzheimer's disease, Parkinson's disease, and other ...
Larry D. Spears +24 more
doaj +1 more source
Plasmalogens participate in very-long-chain fatty acid-induced pathology
, 2009 Peroxisomes are organelles responsible for multiple metabolic pathways including, the biosynthesis of plasmalogens, a class of phospholipids, and the beta-oxidation of very-long-chain fatty acids (VLCFA).
Waterham, Hans R. +4 more
core +1 more source
Determination of Plasmalogen Molecular Species in Hen Eggs
Molecules(1) Background: Plasmalogens are vinyl ether-type glycerophospholipids that are characteristically distributed in neural tissues and are significantly reduced in the brains of individuals with dementia compared to those in healthy subjects, suggesting a ...
Taiki Miyazawa +3 more
doaj +1 more source
Plasmalogen biosynthesis in peroxisomal disorders: fatty alcohol versus alkylglycerol precursors.
Journal of Lipid Research, 1988 In recent years a growing number of inherited diseases have been recognized to originate from an impairment in one or more peroxisomal functions. Since it is well established that the first two steps in the biosynthesis of plasmalogens proceed in ...
G Schrakamp +5 more
doaj +1 more source
ENT1 inhibition links oligodendrocyte lipid metabolism to connectivity in tauopathy
Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.Abstract INTRODUCTION Metabolic dysfunction, altered adenosine signaling, and white matter abnormalities are implicated in tauopathies, but their relationship to network disconnection remains unclear. Myelinating oligodendrocytes may represent a metabolically vulnerable hub linking these processes to circuit dysfunction.
Ching‐Pang Chang +7 more
wiley +1 more source
The discovery of plasmalogen structure
Journal of Lipid Research, 1984 The sequence of events leading to the formulation of the aldehydogenic chain in plasmalogens as an alpha, beta-unsaturated ether is described.
openaire +3 more sources