Results 81 to 90 of about 5,427 (205)

Sterol carrier protein-2 expression alters phospholipid content and fatty acyl composition in L-cell fibroblasts

open access: yesJournal of Lipid Research, 2000
The effects sterol carrier protein-2 (SCP-2) expression on L-cell phospholipid levels and fatty acyl composition was assessed using L-cells transfected with the murine cDNA encoding for either the 15 kDa proSCP-2 or 13.2 kDa SCP-2.
Eric J. Murphy   +2 more
doaj   +1 more source

Hippocampal mediation in the lipid–Alzheimer's disease pathway: A high‐dimensional mediation analysis stratified by APOE and sex

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract INTRODUCTION Systemic lipid dysregulation is a modifiable risk factor for Alzheimer's disease (AD), yet the neuroanatomic pathways through which specific lipids influence AD progression remain poorly delineated. We investigated whether brain structure mediates the relationship between plasma lipids and AD progression, and whether this pathway ...
Yunjia Cao   +6 more
wiley   +1 more source

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 13, Page 3484-3502, July 2026.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl   +3 more
wiley   +1 more source

2-Chlorofatty acids are biomarkers of sepsis mortality and mediators of barrier dysfunction in rats[S]

open access: yesJournal of Lipid Research, 2020
Sepsis is defined as the systemic, dysregulated host immune response to an infection that leads to injury to host organ systems and, often, death. Complex interactions between pathogens and their hosts elicit microcirculatory dysfunction.
Daniel P. Pike   +5 more
doaj   +1 more source

Lipid Dynamics in the Amyloid Cascade Hypothesis: Evaluating the Biological Relevance of In Vitro Models

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle   +6 more
wiley   +1 more source

Plasmalogens in the pathogenesis of glaucomatous optic neuropathy

open access: yes, 2011
Neuronal tissues such as the retina contain high amounts of plasmalogens. One of their particularities is to concentrate polyunsaturated fatty acids (PUFA) before releasing them specifically. Several data from our laboratory suggest that plasmalogens are
Brétillon, Lionel   +5 more
core   +1 more source

The Enzymic Synthesis of Ethanolamine Plasmalogens

open access: yesJournal of Biological Chemistry, 1971
Abstract Enzymic synthesis of ethanolamine plasmalogens from 1-14C-hexadecanol in cell-free systems from Ehrlich ascites and preputial gland tumors of mice is documented. Identification of the ethanolamine plasmalogens is based on the preparation and chromatographic behavior of a number of chemical derivatives that take into account all three positions
F, Snyder, M L, Blank, R L, Wykle
openaire   +2 more sources

Polyunsaturated fatty acids and plasmalogens in diabetics

open access: yes, 2013
PurposePlasmalogens are phospholipids characterized by a vinyl ether bond and a preferential esterification of polyunsaturated fatty acids (PUFA). We have previously shown that the lack of plasmalogens leads to retinal hyper-capillarization.
Brétillon, Lionel   +6 more
core   +2 more sources

Metabolism of serine and ethanolamine plasmalogens in Megasphaera elsdenii [PDF]

open access: yes, 1974
1. 1. Megasphaera elsdenii appears to be a very suitable organism for studies on the metabolism of plasmalogens in anaerobic bacteria due to its extremely high content of both serine and ethanolamine plasmalogen. 2. 2.
Prins, R.A.   +4 more
core   +1 more source

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride–Glucose Index

open access: yesMetabolites
Background: Insulin resistance is a key driver of metabolic syndrome and related disorders, yet its underlying metabolic alterations remain incompletely understood.
Khaled Naja   +3 more
doaj   +1 more source

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