Results 11 to 20 of about 58,767 (165)

Plasminogen Activator – Multifunctional Protein of Plague Pathogen

open access: yesПроблемы особо опасных инфекций, 2016
Yersinia pestis plasminogen activator, a surface protease (Pla) is encoded by species-specific plasmid pPla. This enzyme belongs to outer membrane protein family and has a ß-barrel structure.
L. M. Kukleva, A. V. Boiko
doaj   +1 more source

JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

open access: yesJournal of Biomedical Science, 2011
Background Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer in women are lower than in men. However, it is unknown if 17β-estradiol treatment is sufficient to inhibit prostaglandin E2 (PGE2)-induced cellular
Chen Wei-Kung   +9 more
doaj   +1 more source

Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis. [PDF]

open access: yesPLoS ONE, 2012
The molecular mechanisms underlying cerebral angiogenesis have not been fully investigated. Using primary mouse brain endothelial cells (MBECs) and a capillary-like tube formation assay, we investigated whether the sonic hedgehog (Shh) signaling pathway ...
Hua Teng   +6 more
doaj   +1 more source

Relationship between plasminogen activator inhibitor type-1 (PAI-1) gene polymorphisms and osteoporosis in Turkish women

open access: yesClinics, 2012
OBJECTIVE: The development of osteoporosis is associated with several risk factors, such as genetic structures that affect bone turnover and bone mass. The impact of genetic structures on osteoporosis is not known.
Merih Ozgen   +8 more
doaj   +1 more source

Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship

open access: yesDiabetology & Metabolic Syndrome, 2022
Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue.
Gaber El-Saber Batiha   +6 more
doaj   +1 more source

Plasminogen influence on the PAI-1 release by human platelets [PDF]

open access: yesThe Ukrainian Biochemical Journal
РАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova   +3 more
doaj   +1 more source

Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients.

open access: yesFolia Histochemica et Cytobiologica, 2008
Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced sputum of house dust mite allergic asthmatics (HDM-AAs).
Sebastian Zukowski   +3 more
doaj   +1 more source

Plasminogen activator inhibitor-1 in the evolution of stroke [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2004
Fibrinolytic activity in the acute stroke was examined by monitoring the level of plasminogen activator inhibitor-1 (PAI-1), as one of the indicators of fibrinolytic activity.
Jovanović Zagorka B.   +8 more
doaj   +1 more source

Plasminogen activator inhibitor-1 (PAI-1) expression in endometriosis.

open access: yesPLoS ONE, 2019
PurposeDeep infiltrating endometriosis (DIE) is defined as an endometriotic lesion penetrating to a depth of >5 mm and is associated with pelvic pain, but the underlying mechanisms are unclear.
Fahad T Alotaibi   +8 more
doaj   +1 more source

Impact of PAI-1 4G/5G and C > G polymorphisms in acute ST elevation myocardial infarction and stable angina patients: A single center Egyptian study

open access: yesEgyptian Journal of Medical Human Genetics, 2018
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation and fibrinolysis have been proposed as risk factors for coronary artery disease (CAD).
Hanan Al-Wakeel   +3 more
doaj   +1 more source

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