Results 21 to 30 of about 60,177 (254)
Clinics, 2012 OBJECTIVE: The development of osteoporosis is associated with several risk factors, such as genetic structures that affect bone turnover and bone mass. The impact of genetic structures on osteoporosis is not known.
Merih Ozgen +8 more
doaj +1 more source
Plasminogen influence on the PAI-1 release by human platelets [PDF]
The Ukrainian Biochemical JournalРАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova +3 more
doaj +1 more source
Tissue Plasminogen Activator, Plasminogen Activator Inhibitor-1, and Tissue Plasminogen Activator/Plasminogen Activator Inhibitor-1 Complex as Risk Factors for the Development of a First Stroke [PDF]
Stroke, 2000 Background and Purpose —Abnormalities in the fibrinolytic system have been associated with an increased risk for stroke in a few studies. This study was designed to test whether plasma levels of tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1), and tPA/PAI-1 complex could predict a first-ever stroke.
L, Johansson +5 more
openaire +2 more sources
Plasminogen activator inhibitor-1 and haemostasis in obesity [PDF]
Proceedings of the Nutrition Society, 2001 The connection between obesity and disordered haemostasis is well established, but incompletely understood. There is a strong link between inhibition of fibrinolysis and obesity, and elevation of the plasma inhibitor, plasminogen activator inhibitor-1 (PAI-1), is regarded as a central factor.
N J, Mutch, H M, Wilson, N A, Booth
openaire +2 more sources
Folia Histochemica et Cytobiologica, 2008 Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced sputum of house dust mite allergic asthmatics (HDM-AAs).
Sebastian Zukowski +3 more
doaj +1 more source
Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship
Diabetology & Metabolic Syndrome, 2022 Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue.
Gaber El-Saber Batiha +6 more
doaj +1 more source
Plasminogen activator inhibitor-1 (PAI-1) expression in endometriosis.
PLoS ONE, 2019 PurposeDeep infiltrating endometriosis (DIE) is defined as an endometriotic lesion penetrating to a depth of >5 mm and is associated with pelvic pain, but the underlying mechanisms are unclear.
Fahad T Alotaibi +8 more
doaj +1 more source
Вестник анестезиологии и реаниматологииThe fibrinolysis system is one of the most important regulators of homeostasis and participates in maintaining stable blood flow. The key element of this system is the balance of plasminogen activators and inhibitors, which can be considered as markers ...
M. M. Tanashyan +4 more
doaj +1 more source
Вестник анестезиологии и реаниматологииThe fibrinolysis system is one of the most important regulators of homeostasis and participates in maintaining stable blood flow. The key element of this system is the balance of plasminogen activators and inhibitors, which can be considered as markers ...
M. M. Tanashyan +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source