Results 31 to 40 of about 113,706,673 (279)

Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational Study

open access: yes, 2021
Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational ...
Giuseppe Lippi   +13 more
core   +1 more source

Tissue Plasminogen Activator, Plasminogen Activator Inhibitor-1, and Tissue Plasminogen Activator/Plasminogen Activator Inhibitor-1 Complex as Risk Factors for the Development of a First Stroke [PDF]

open access: yesStroke, 2000
Background and Purpose —Abnormalities in the fibrinolytic system have been associated with an increased risk for stroke in a few studies. This study was designed to test whether plasma levels of tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1), and tPA/PAI-1 complex could predict a first-ever stroke.
L, Johansson   +5 more
openaire   +2 more sources

Plasminogen influence on the PAI-1 release by human platelets [PDF]

open access: yesThe Ukrainian Biochemical Journal
РАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova   +3 more
doaj   +1 more source

Plasminogen activator inhibitor-1 and haemostasis in obesity [PDF]

open access: yesProceedings of the Nutrition Society, 2001
The connection between obesity and disordered haemostasis is well established, but incompletely understood. There is a strong link between inhibition of fibrinolysis and obesity, and elevation of the plasma inhibitor, plasminogen activator inhibitor-1 (PAI-1), is regarded as a central factor.
N J, Mutch, H M, Wilson, N A, Booth
openaire   +2 more sources

Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis [PDF]

open access: yes, 2010
Background: Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires degradation of the extracellular matrix, which is fulfilled by membrane-associated ...
Olivier Gires   +31 more
core   +2 more sources

Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients.

open access: yesFolia Histochemica et Cytobiologica, 2008
Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced sputum of house dust mite allergic asthmatics (HDM-AAs).
Sebastian Zukowski   +3 more
doaj   +1 more source

Plasminogen activator inhibitor-1 (PAI-1) expression in endometriosis.

open access: yesPLoS ONE, 2019
PurposeDeep infiltrating endometriosis (DIE) is defined as an endometriotic lesion penetrating to a depth of >5 mm and is associated with pelvic pain, but the underlying mechanisms are unclear.
Fahad T Alotaibi   +8 more
doaj   +1 more source

Thrombotic risk markers: tissue plasminogen activator/tissue plasminogen activator inhibitor-1 complex (Part 1)

open access: yesВестник анестезиологии и реаниматологии
The fibrinolysis system is one of the most important regulators of homeostasis and participates in maintaining stable blood flow. The key element of this system is the balance of plasminogen activators and inhibitors, which can be considered as markers ...
M. M. Tanashyan   +4 more
doaj   +1 more source

Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship

open access: yesDiabetology & Metabolic Syndrome, 2022
Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue.
Gaber El-Saber Batiha   +6 more
doaj   +1 more source

Thrombotic risk markers: tissue plasminogen activator-inhibitor complex/ tissue plasminogen activator inhibitor-1 (part 2)

open access: yesВестник анестезиологии и реаниматологии
The fibrinolysis system is one of the most important regulators of homeostasis and participates in maintaining stable blood flow. The key element of this system is the balance of plasminogen activators and inhibitors, which can be considered as markers ...
M. M. Tanashyan   +4 more
doaj   +1 more source

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