Results 11 to 20 of about 54,262 (254)
Терапевтический архив, 2012 Aim. To estimate the levels of of plasminogen (Pg) and inhibitor of plasminogen activators of type 1 (IPA-1) in patients with antiphospholipid syndrome (APS) and to reveal correlations between their content and clinical-laboratory characteristics of APS.
E V Ostryakova +10 more
doaj +1 more source
Tissue Plasminogen Activator [PDF]
New England Journal of Medicine, 1989 Coronary thrombolysis has been proved to be beneficial in the treatment of myocardial infarction. Much attention has been focused on tissue-type plasminogen activator (t-PA) as a fibrinolytic agent. This article will discuss the unique properties of t-PA and the role of the critical care nurse in providing the safe delivery of t-PA.
openaire +4 more sources
Contribution of plasminogen activation towards the pathogenic potential of oral streptococci. [PDF]
PLoS ONE, 2010 Oral streptococci are a heterogeneous group of human commensals, with a potential to cause serious infections. Activation of plasminogen has been shown to increase the virulence of typical human pathogenic streptococci such as S. pneumoniae.
Andreas Itzek +6 more
doaj +1 more source
Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity [PDF]
, 2009 Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
AG Barbour +59 more
core +10 more sources
Proteolytic enzyme and adiponectin receptors as potential targets for COVID-19 therapy
Кардиоваскулярная терапия и профилактика, 2021 The coronavirus disease 2019 (COVID-19) pandemic requires not only the creation of vaccines to prevent the spread of the disease, but also the development of novel drugs aimed at reducing viral load, suppressing an excessive immune response and ...
K. A. Rubina +5 more
doaj +1 more source
Annals of Cardiac Anaesthesia, 2020 Prosthetic valve thrombosis (PVT) is a rare but life-threatening complication. It has an incidence of 6.1% in developing countries and 0.3%–1.3% in developed countries.
Hasan Haghaninejad +2 more
doaj +1 more source
Location, location, location: Fibrin, cells, and fibrinolytic factors in thrombi
Frontiers in Cardiovascular Medicine, 2023 Thrombi are heterogenous in nature with composition and structure being dictated by the site of formation, initiating stimuli, shear stress, and cellular influences. Arterial thrombi are historically associated with high platelet content and more tightly
Anuj Narwal +2 more
doaj +1 more source
Fibrinolysis and bleeding of unknown cause
Research and Practice in Thrombosis and Haemostasis, 2021 Patients with bleeding of unknown cause (BUC) present with a variety of mild to moderate bleeding symptoms, but no hemostatic abnormalities can be found. Hyperfibrinolysis is rarely evaluated as the underlying cause for bleeding in clinical practice, and
Dino Mehic +3 more
doaj +1 more source
Journal of Baghdad College of Dentistry, 2022 Background: Monocyte chemotactic protein-1 (MCP-1) is a chemokine expressed by inflammatory and endothelial cells. It has a crucial role in initiating, regulating, and mobilizing monocytes to active sites of periodontal inflammation.
Safa A Hamad , Maha S Mahmood
doaj +1 more source
Interaction with human plasminogen system turns on proteolytic activity in Streptococcus agalactiae and enhances its virulence in a mouse model [PDF]
, 2001 Interactions of several microbial pathogens with the plasminogen system increase their invasive potential. In this study, we show that Streptococcus agalactiae binds human plasminogen which can be subsequently activated to plasmin, thus generating a ...
Vanessa Magalhaes +6 more
core +4 more sources