Results 31 to 40 of about 648 (173)
Hypoxia‐Inducible Factor in Thyroid Carcinoma
Journal of Thyroid Research, Volume 2011, Issue 1, 2011., 2011 Intratumoural hypoxia (low oxygen tension) is associated with aggressive disease and poor prognosis. Hypoxia‐inducible factor‐1 is a transcription factor activated by hypoxia that regulates the expression of genes that promote tumour cell survival, progression, metastasis, and resistance to chemo/radiotherapy.
Natalie Burrows +5 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 5, Issue 1, Page 3-15, 2008., 2008 Agaricus blazei Murrill (ABM) popularly known as ‘Cogumelo do Sol’ in Brazil, or ‘Himematsutake’ in Japan, is a mushroom native to Brazil, and widely cultivated in Japan for its medicinal uses, so it is now considered as one of the most important edible and culinary‐medicinal biotechnological species.
F. Firenzuoli, L. Gori, G. Lombardo
wiley +1 more source
Structure‐Activity Relationships of Synthetic Coumarins as HIV‐1 Inhibitors
Bioinorganic Chemistry and Applications, Volume 2006, Issue 1, 2006., 2006 HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti‐HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV. A lot of structurally different coumarins were found to display potent anti‐HIV activity.
I. Kostova +3 more
wiley +1 more source
Cross-Talk Between Clinical and Host-Response Parameters of Periodontitis in Smokers [PDF]
, 2016 Background and Objective Periodontal diseases are a major public health concern leading to tooth loss and have also been shown to be associated with several chronic systemic diseases.
Al-Sabbagh, Mohanad +4 more
core +2 more sources
Urokinase and urokinase receptor in the urinary tract of the dog [PDF]
, 2005 Urokinase (uPA) and urokinase receptor (uPAR) are present in the urinary tract of people, mice, rats and cows. The presence of urokinase and urokinase receptor in the urinary tract of dogs has not been documented. Documenting the presence of uPA and uPAR
Bailey, Trina Racquel
core +2 more sources
The efficacy of tranexamic acid in reducing perioperative blood loss in secondary scoliosis surgery [PDF]
, 2023 Background: Secondary scoliosis occurs in children as a result of various underlying diseases and, due to its strong progression, is corrected surgically via a posterior spinal fusion (PSF).
Güven, Ali Eren
core +1 more source
Inactivation of Plasminogen Activator Inhibitor-1 by Specific Proteolysis with Stromelysin-1 (MMP-3) [PDF]
Journal of Biological Chemistry, 2000 Matrix metalloproteinase-3 (MMP-3 or stromelysin-1) specifically hydrolyzes the Ser(337)-Ser(338) (P10-P9) and Val(341)-Ile(342) (P6-P5) peptide bonds in human plasminogen activator inhibitor-1 (PAI-1). Cleavage is completely abolished in the presence of the metal chelators EDTA or 1,10-phenanthroline. A stabilized active PAI-1 variant was also cleaved
H R, Lijnen +4 more
openaire +2 more sources
APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats [PDF]
, 2018 APX3330 is a selective inhibitor of APE1/Ref-1 redox activity. In this study, we investigate the therapeutic effects and underlying mechanisms of APX3330 treatment in type one diabetes mellitus (T1DM) stroke rats. Adult male Wistar rats were induced with
Chen, Jieli +8 more
core +1 more source
Health Science Reports, Volume 7, Issue 6, June 2024.Abstract Background and Aims Lung cancer is ranked as the second most prevalent form of cancer worldwide. Nonsmall cell lung cancer (NSCLC) represents the predominant histological subtype. Research suggests that one‐third of lung cancer patients also experiencing depression. Antidepressants play an indispensable role in the management of NSCLC. Despite
Huan Gui +3 more
wiley +1 more source
Cleavage of C3 by Neutral Proteases from Granulocytes in Pleural Empyema [PDF]
, 2017 The possibility of direct inactivation of C3 by granular enzymes from polymorphonuclear leukocytes(PMNLs) in pleural empyema was examined. As a group, pleural empyema from 10 patients with purulent effusions and a positive bacteriologic culture cleaved ...
Nydegger, U. E. +3 more
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