Results 21 to 30 of about 433,927 (377)
Neurobiology of DiseaseIschemic stroke (IS) is a leading cause of global morbidity and mortality. A critical strategy for improving the prognosis of IS involves mitigating neuronal loss to enhance neuroplasticity, with microglia playing a vital role in neuronal survival.
Xi-Yue Zhang +9 more
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CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development. [PDF]
J Immunol, 2017 Patel PS, Kearney JF.
europepmc +3 more sources
FEBS Letters, 2021 Streptococcus pneumoniae causes pneumonia by infecting the alveolar epithelium via binding to host receptors, such as the platelet‐activating factor receptor (PAFR).
Noriaki Kamio +4 more
semanticscholar +1 more source
Cells, 2021 The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development.
Eileen Deuster +14 more
doaj +1 more source
The effect of PAFR on cisplatin sensitivity in ovarian cancer cells and its mechanism [PDF]
Zhongguo aizheng zazhi, 2021 Background and purpose: The current treatment of ovarian cancer is surgery and adjuvant platinum-based chemotherapy. However, relapse and drug resistance are common.
YU Yi, CONG Qing, XU Congjian, JIANG Wei
doaj +1 more source
UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment
Frontiers in Immunology, 2022 Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis.
Timothy C. Frommeyer +10 more
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Frontiers in Oncology, 2020 Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase widely expressed in cervical tumors, being correlated with adverse clinical outcomes. EGFR may be activated by a diversity of mechanisms, including transactivation by G-protein coupled
Juliana L. Souza +6 more
doaj +1 more source
Platelet-activating factor: receptors and signal transduction [PDF]
Biochemical Journal, 1993 During the past two decades, studies describing the chemistry and biology of PAF have been extensive. This potent phosphoacylglycerol exhibits a wide variety of physiological and pathophysiological effects in various cells and tissues. PAF acts, through specific receptors and a variety of signal transduction systems, to elicit diverse biochemical ...
W, Chao, M S, Olson
openaire +2 more sources
Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]
, 2018 Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A. +6 more
core +1 more source
Molecules, 2019 Ginkgolides are the major active component of Ginkgo biloba for inhibition of platelet activating factor receptor. An azide-alkyne Huisgen cycloaddition reaction was used to introduce a triazole nucleus into the target ginkgolide molecules.
Jian Cui +5 more
doaj +1 more source