Results 31 to 40 of about 3,850 (157)
Biomedicines, 2022 The endothelium plays an important role in the transcytosis of lipoproteins. According to one of the theories, endothelial injury is a triggering factor for the development of atherosclerosis, and intracellular structures, including components of the ...
Anton S. Shakhov, Irina B. Alieva
doaj +1 more source
Cells, 2021 Cancer-specific plectin (CSP) is a pro-tumorigenic protein selectively expressed on the cell surface of major cancers, including ovarian cancer (OC). Despite its assessable localization, abundance, and functional significance, the therapeutic efficacy of
Samantha M. Perez +3 more
doaj +1 more source
Occurrence and immunolocalization of plectin in tissues. [PDF]
The Journal of cell biology, 1983 Various tissues from rat were examined for the occurrence and cellular localization of plectin, a 300,000-dalton polypeptide component present in intermediate filament-enriched cytoskeletons prepared from cultured cells by treatment with nonionic detergent and high salt solution.
G, Wiche +4 more
openaire +2 more sources
Frontiers in Oncology, 2021 Circulating tumor cells (CTCs) are useful biomarkers of many solid tumors, but are infrequently detected in early stage pancreatic ductal adenocarcinomas (PDACs). The first drainage of pancreatic venous blood flow come to portal vein and pass through the
Byeong Geun Song +15 more
doaj +1 more source
Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells
Cells, 2020 Elucidation of the mitochondrial regulatory mechanisms for the understanding of muscle bioenergetics and the role of mitochondria is a fundamental problem in cellular physiology and pathophysiology. The cytoskeleton (microtubules, intermediate filaments,
Andrey V. Kuznetsov +5 more
doaj +1 more source
Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. [PDF]
PLoS Medicine, 2008 BackgroundPancreatic ductal adenocarcinoma (PDAC) carries an extremely poor prognosis, typically presenting with metastasis at the time of diagnosis and exhibiting profound resistance to existing therapies.
Kimberly A Kelly +8 more
doaj +1 more source
Plectin isoforms as organizers of intermediate filament cytoarchitecture [PDF]
BioArchitecture, 2011 Intermediate filaments (IFs) form cytoplamic and nuclear networks that provide cells with mechanical strength. Perturbation of this structural support causes cell and tissue fragility and accounts for a number of human genetic diseases. In recent years, important additional roles, nonmechanical in nature, were ascribed to IFs, including regulation of ...
Wiche, Gerhard, Winter, Lilli
openaire +3 more sources
Brain Circulation, 2016 Objective: In the central nervous system (CNS), β4 integrin is predominantly expressed by endothelial cells lining arterioles. As β4 integrin plays an essential role in epithelial tissues, organizing structural proteins into specialized adhesive ...
Jennifer V Welser-Alves +3 more
doaj +1 more source
Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods
Advanced NanoBiomed Research, EarlyView.Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria +5 more
wiley +1 more source
Peptide‐based responsive molecular fluorescent probes for precision oncology
Responsive Materials, EarlyView.Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang +6 more
wiley +1 more source