Results 61 to 70 of about 4,450 (185)

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

International Journal of Cosmetic Science, Volume 48, Issue 3, Page 600-634, June 2026.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec, Daria Terescenco, Ecaterina Gore   +2 more
wiley   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, Volume 604, Issue 11, Page 4387-4404, 1 June 2026.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Proteomic Analysis of Corpora Amylacea Extracted From Post‐mortem Brain of MAiD‐end‐of‐life Sporadic ALS Patients

Brain and Behavior, Volume 16, Issue 5, May 2026.
Corpora amylacea extracted from the brain of ALS patients carry a specific proteomic signature. Created in BioRender. Paquet, A. (2025) https://BioRender.com/x6dh8e0 ABSTRACT Purpose Corpora amylacea (CA) are starch‐like inclusions that accumulate in the central nervous system (CNS) with aging and are enriched in neurodegenerative conditions, including
Alexandre Paquet, Lydia Touzel‐Deschênes, Vincent Roy, Stephan Saikali, Nicolas Dupré, François Gros‐Louis   +5 more
wiley   +1 more source

Plectin-1 as a Novel Biomarker for Pancreatic Cancer [PDF]

Clinical Cancer Research, 2011
Abstract Purpose: We are in great need of specific biomarkers to detect pancreatic ductal adenocarcinoma (PDAC) at an early stage, ideally before invasion. Plectin-1 (Plec1) was recently identified as one such biomarker. However, its suitability as a specific biomarker for human pancreatic cancer, and its usability as an imaging ...
Bausch, Dirk, Thomas, Stephanie, Mino-Kenudson, Mari, Fernandez-del-Castillo, Carlos, Bauer, T. W., Williams, M., Warshaw, Andrew Louis, Thayer, Sarah P., Kelly, Kimberly A.   +8 more
openaire   +3 more sources

Glu20Ter Variant in PLEC 1f Isoform Causes Limb-Girdle Muscle Dystrophy with Lung Injury

Frontiers in Neurology, 2017
Plectinopathies are orphan diseases caused by PLEC gene mutations. PLEC is encoding the protein plectin, playing a role in linking cytoskeleton components in various tissues.
Roman V. Deev, Roman V. Deev, Sergei N. Bardakov, Mikhail O. Mavlikeev, Ivan A. Yakovlev, Ivan A. Yakovlev, Ivan A. Yakovlev, Zoya R. Umakhanova, Patimat G. Akhmedova, Raisat M. Magomedova, Irina A. Chekmaryeva, Gimat D. Dalgatov, Artur A. Isaev   +12 more
doaj   +1 more source

The atomic structure of human dystrophin spectrin‐like repeat 24

Acta Crystallographica Section F, Volume 82, Issue 5, Page 184-193, May 2026.
The atomic structure of human dystrophin spectrin‐like repeat 24 was determined at 2.14 Å resolution.The structure of spectrin‐like repeat 24 of human dystrophin was determined at 2.5 Å effective resolution. The structure exhibits a three‐helix bundle fold, common to all spectrin‐repeat family members, and shares a high degree of homology with existing
Oakley Streeter, Ke Shi, Hannah Bui, Hideki Aihara, James M. Ervasti, Robert Evans III, Joseph M. Muretta   +6 more
wiley   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 4, Page 391-418, April 2026.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Loss of interaction between plectin and type XVII collagen results in epidermolysis bullosa simplex [PDF]

, 2017
Plectin is a linker protein that interacts with intermediate filaments and 4 integrin in hemidesmosomes of the epidermal basement membrane zone (BMZ).
Hirako, Yoshiaki, Yoshiaki Hirako, Mika Watanabe, Nishimura, Machiko, Shinkuma, Satoru, Hideki Nakamura, Hiroshi Shimizu, Izumi, Kentaro, Nakamura, Hideki, Satoru Shinkuma, Natsuga, Ken, Kentaro Izumi, Shimizu, Hiroshi, Ken Natsuga, Nishie, Wataru, Watanabe, Mika, Wataru Nishie, Machiko Nishimura   +17 more
core   +1 more source

Molecular Responses to Climate Change: How Warming and Acidification Reshape the Proteome and Phosphoproteome of the Endangered Mira Chub

Ecology and Evolution, Volume 16, Issue 3, March 2026.
ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno, Jonas Grossmann, Laura Kunz, Antje Dittmann, Vitor C. Sousa, Romana Santos   +5 more
wiley   +1 more source