Results 111 to 120 of about 3,583 (200)

Funktionen von Pleiotrophin in der Regulation der Hämatopoese

, 2010
Hematopoietic stem cells (HSC) reside in specialized microenvironments, which are crucial for the strict regulation of HSC function. In this thesis, the role of the cytokine Pleiotrophin (Ptn) in the regulation of hematopoiesis and HSC functions was ...
Kröger, Monika
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Pleiotrophin Maintenance of PDGFRα-defined Fetal Human Oligodendrocyte Progenitor Cell Fate

, 2020
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Interdepartmental Graduate Program in Neuroscience, 2012.Studies of cell genesis in the adult vertebrate brain and subsequent isolation, relative distribution, and lineage
McClain, Crystal R., Goldman, Steven A.
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Pleiotrophin Gene Therapy for Peripheral Ischemia: Evaluation of Full-Length and Truncated Gene Variants

, 2013
Pleiotrophin (PTN) is a growth factor with both pro-angiogenic and limited pro-tumorigenic activity. We evaluated the potential for PTN to be used for safe angiogenic gene therapy using the full length gene and a truncated gene variant lacking the domain
Lee, Randall, Haddad, DJ, Clifford, BT, Thomas, AE, Ye, W, Mok, PY, Springer, Matthew, Kapasi, NK, Usui, M, Saini, SA, Danforth, OM, Fang, Q   +11 more
core  

Recombinant Pleiotrophin [PDF]

, 2020
openaire   +1 more source

Functions of pleiotrophin in the regulation of hematopoiesis.

, 2010
Hematopoietic stem cells (HSC) reside in specialized microenvironments, which are crucial for the strict regulation of HSC function. In this thesis, the role of the cytokine Pleiotrophin (Ptn) in the regulation of hematopoiesis and HSC functions was ...
Kröger, M.
core  

PTN activity in quiescent neural stem cells mediates Shank3 overexpression-induced manic behavior

Nature Communications
Mania is a complex psychiatric disease characterized by hyperactivity, elevated mood and reduced anxiety. Despite extensive studies on the mechanism of the manic episodes, the molecular targets that control manic pathogenesis remain largely unclear. Here,
Hongwon Kim, Byounggook Cho, Hyung Kyu Kim, Soi Kang, Saemin An, Daeyeol Kwon, Hee Young Kim, Jongpil Kim   +7 more
doaj   +1 more source

Pleiotrophin antagonizes Brd2 during neuronal differentiation.

Journal of cell science, 2014
Bromodomain-containing protein 2 (Brd2) is a BET family chromatin adaptor required for expression of cell-cycle-associated genes and therefore involved in cell cycle progression. Brd2 is expressed in proliferating neuronal progenitors, displays cell-cycle-stimulating activity and, when overexpressed, impairs neuronal differentiation.
García-Gutiérrez, Pablo, Juárez-Vicente, Francisco, Wolgemuth, Debra J., García-Domínguez, Mario   +3 more
openaire   +2 more sources

Evidence of the role of Midkine and Pleiotrophin in the pathogenesis of Familial Mediterranean Fever. [PDF]

Eur J Pediatr
Abdallah ZY, Eldeen GN, Sokkar MF, Abdelkawy RFM, Lotfy RS, Hussein SH, Hamed K, El-Bassyouni HT.   +7 more
europepmc   +1 more source

<i>ICAM2</i> loss drives 5-fluorouracil resistance <i>via</i> TGF-β/Smad/SP1/PTN-dependent apoptosis evasion and macrophage remodeling in gastric cancer. [PDF]

World J Gastroenterol
Tang XC, Chen ZJ, Chen CY, Qiu J, Huang JT, Tan RC, Li WY, Chen H, Yang ZL.   +8 more
europepmc   +1 more source

Exogenous pleiotrophin applied to lesioned nerve impairs muscle reinnervation.

, 2006
Pleiotrophin (PTN) is a heparin-binding growth factor involved in nerve regeneration after peripheral nerve injury. After crush injury, PTN is found in distal nerve segments in several non-neural cell types, including Schwann cells, macrophages, and ...
Ferry, A., Blondet, B., Carpentier, G., Courty, Jose   +3 more
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