Results 91 to 100 of about 3,583 (200)

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling

open access: yesThe Journal of Clinical Investigation, 2022
Dysfunction of protein trafficking has been intensively associated with neurological diseases, including neurodegeneration, but whether and how protein transport contributes to oligodendrocyte (OL) maturation and myelin repair in white matter injury ...
Zhixiong Liu   +21 more
doaj   +1 more source

The Tropism of Pleiotrophin: Orchestrating Glioma Brain Invasion [PDF]

open access: yesCell, 2017
The lateral ventricle (LV) is a preferential location for brain tumor spread; however, the instructive cues responsible for this unique tropism were previously unknown. In this issue, Qin et al. elucidate the underlying mechanism, demonstrating that LV-neural progenitors secrete a pleiotrophin (PTN)-containing complex, which attracts glioma cells ...
openaire   +2 more sources

Image_6_Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.jpeg

open access: yes, 2022
Astrocytes are the most abundant glial cells in the central nervous system (CNS) with the capacity to sense and react to injury and inflammatory events. While it has been widely documented that astrocytes can exert tissue-degenerative functions, less is ...
Ulrike Naumann (123144)   +6 more
core   +1 more source

Methylcobalamin, but Not Methylprednisolone or Pleiotrophin, Accelerates the Recovery of Rat Biceps after Ulnar to Musculocutaneous Nerve Transfer

open access: yes, 2011
Using ulnar nerve as donor and musculocutaneous nerve as recipient we recently demonstrated that end-to-end neurorrhaphy in young adult male Wistar rats resulted in good recovery following protracted survival.
LIAO, WEN-CHIEH;CHEN, JENG-RUNG;WANG, YUEH-JAN;TSENG, GUO-FANG   +1 more
core   +2 more sources

Image_4_Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.jpeg

open access: yes, 2022
Astrocytes are the most abundant glial cells in the central nervous system (CNS) with the capacity to sense and react to injury and inflammatory events. While it has been widely documented that astrocytes can exert tissue-degenerative functions, less is ...
Ulrike Naumann (123144)   +6 more
core   +1 more source

Pleiotrophin Exerts Its Migration and Invasion Effect through the Neuropilin-1 Pathway

open access: yesNeoplasia: An International Journal for Oncology Research, 2015
Pleiotrophin (PTN) is a pleiotropic growth factor that exhibits angiogenic properties and is involved in tumor growth and metastasis. Although it has been shown that PTN is expressed in tumor cells, few studies have investigated its receptors and their ...
Rania Elahouel   +8 more
doaj   +1 more source

Pleiotrophin family gene and protein expression in a sheep tooth socket model of bone healing

open access: yes, 2020
Resorption of alveolar bone after tooth extraction is a common problem. Bone replacement materials are used to enhance socket healing and reduce alveolar bone loss.
Nobakht, Saeideh
core  

Image_5_Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.jpeg

open access: yes, 2022
Astrocytes are the most abundant glial cells in the central nervous system (CNS) with the capacity to sense and react to injury and inflammatory events. While it has been widely documented that astrocytes can exert tissue-degenerative functions, less is ...
Ulrike Naumann (123144)   +6 more
core   +1 more source

Pleiotrophin promotes perineural invasion in pancreatic cancer

open access: yesWorld Journal of Gastroenterology, 2013
Perineural invasion (PNI) in pancreatic cancer is an important cause of local recurrence, but little is known about its mechanism. Pleiotrophin (PTN) is an important neurotrophic factor. It is of interest that our recent experimental data showed its involvement in PNI of pancreatic cancer.
Jun, Yao   +3 more
openaire   +2 more sources

Image_1_Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.jpeg

open access: yes, 2022
Astrocytes are the most abundant glial cells in the central nervous system (CNS) with the capacity to sense and react to injury and inflammatory events. While it has been widely documented that astrocytes can exert tissue-degenerative functions, less is ...
Ulrike Naumann (123144)   +6 more
core   +1 more source

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