Results 21 to 30 of about 7,658 (197)
, 2022 Vascularization is one of the key challenges in tissue regeneration. Nascent vessels formed by endothelial cells in initiation stage are immature and unstable.
Chengfei Zhang (9053432) +2 more
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Evolution and Diversity of Semaphorins and Plexins in Choanoflagellates [PDF]
Genome Biology and Evolution, 2021 Abstract Semaphorins and plexins are cell surface ligand/receptor proteins that affect cytoskeletal dynamics in metazoan cells. Interestingly, they are also present in Choanoflagellata, a class of unicellular heterotrophic flagellates that forms the phylogenetic sister group to Metazoa. Several members of choanoflagellates are capable of
Chrystian Junqueira Alves +7 more
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, 2022 The recruitment of mural cells is critical for stabilization of nascent vessels. Stem cells from human exfoliated deciduous teeth (SHED) are considered to have mural cell-like properties.
Qixin Chen (9391475) +3 more
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Modeling transmembrane domain dimers/trimers of plexin receptors: implications for mechanisms of signal transmission across the membrane. [PDF]
PLoS ONE, 2015 Single-pass transmembrane (TM) receptors transmit signals across lipid bilayers by helix association or by configurational changes within preformed dimers. The structure determination for such TM regions is challenging and has mostly been accomplished by
Liqun Zhang +2 more
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Semaphorins and Plexins in Kidney Disease [PDF]
Nephron, 2016 Semaphorins are soluble or membrane-bound cues, which control multiple aspects of cell-cell communication, differentiation, morphology and function. Most of their effects are mediated by a family of transmembrane receptors called plexins. Semaphorins and plexins have emerged as central regulators of diverse physiological and pathophysiological ...
Xia , J., Worzfeld, T.
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The IκB kinase complex is required for plexin-B-mediated activation of RhoA. [PDF]
PLoS ONE, 2014 Plexins are widely expressed transmembrane proteins that mediate the cellular effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still poorly understood.
Matthias Zielonka +3 more
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Semaphorin 4D Induces Vasculogenic Differentiation of Dental Pulp Stem Cells
Dentistry Journal, 2023 This work aimed to evaluate the effect of Semaphorin 4D (SEMA4D) signaling through Plexin B1 on the vasculogenic differentiation of dental pulp stem cells.
Najla Al Turkestani +2 more
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Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation
Molecular and Cellular Neuroscience, 2023 Abstract Synapse formation in the mammalian brain is a complex and dynamic process requiring coordinated function of dozens of molecular families such as cell adhesion molecules (CAMs) and ligand-receptor pairs (Ephs/Ephrins, Neuroligins/Neurexins, Semaphorins/Plexins).
Susannah S. Adel +6 more
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SOX4 transcriptionally regulates multiple SEMA3/plexin family members and promotes tumor growth in pancreatic cancer. [PDF]
PLoS ONE, 2012 Semaphorin signaling through Plexin frequently participates in tumorigenesis and malignant progression in various types of cancer. In particular, the role of semaphorin signaling in pancreatic ductal adenocarcinoma (PDAC) remains unexplored, despite a ...
Hsin-Yi Huang +6 more
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Mechanismen der Mitosespindelorientierung durch Plexin-B2
, 2021 Cells show certain asymmetries in morphology and molecular organization, a characteristic that is known as cell polarity. Polarity is generally regulated by protein complexes and Rho GTPases like Cdc42, Rho or Rac.
Fernández Baldovinos, Javier
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