Results 131 to 140 of about 2,043 (169)

The Role of Semaphorin 6D (Sema6D) in Non-Muscle-Invasive Bladder Cancer-A Preliminary Study on Human Plasma and Urine. [PDF]

open access: yesBiomedicines
Purpurowicz P   +5 more
europepmc   +1 more source

Increased semaphorin, neuropilin, and plexin expression plays a role in recovery after traumatic brain injury. [PDF]

open access: yesMetab Brain Dis
Okan A   +5 more
europepmc   +1 more source

Case report: Germline CHEK2 mutation is associated with a giant cell glioblastoma. [PDF]

open access: yesFront Oncol
Bi Y   +9 more
europepmc   +1 more source
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Semaphorins and plexins as therapeutic targets

Nature Reviews Drug Discovery, 2014
Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions and are involved in cell-cell communication. Most of the effects of semaphorins are mediated by plexins. Work over the past decade has revealed crucial functions of the semaphorin-plexin system in mammalian physiology. It has also become clear that semaphorins and
Stefan Offermanns   +2 more
exaly   +3 more sources

Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains

Biochemical and Biophysical Research Communications, 2003
Semaphorin 3A (Sema3A) is a member of semaphorins and functions as an axonal repulsive guidance molecule. Neuropilin-1 and plexin-As form receptor complexes for Sema3A and plexin-As are thought to initiate the intracellular signaling cascade. However, the molecule by which plexin-As transduce their signal is not well understood.
Hiroshi, Usui   +3 more
openaire   +2 more sources

The expression of plexins during mouse embryogenesis

Gene Expression Patterns, 2005
Plexins are large transmembrane proteins that are receptors for semaphorins, either alone or in a complex with neuropilin-1 or -2. Nine different mouse plexins have been found: Plexin-A1-4, -B1-3, -C1 and -D1. The expression and function of plexins in non-neuronal tissues has been poorly characterized, although Plexin-A1 has been shown to have a role ...
Hannu Sariola
exaly   +3 more sources

Plexins are partners for neuropilins

Science Signaling, 1999
Membrane-bound and secreted semaphorins regulate a number of cell adhesion processes including axon guidance in the nervous system. However, little is known about the receptors to which they bind. Although neuropilins bind to secreted class 3 semaphorins (Sema3), it is thought that a coreceptor might be required to transduce Sema3 signals
openaire   +2 more sources

Plexins: axon guidance and signal transduction

Cellular and Molecular Life Sciences, 2005
Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as semaphorins, ephrins and netrin. Plexins function as receptors for the repulsive axonal guidance molecules semaphorins.
M, Negishi, I, Oinuma, H, Katoh
openaire   +2 more sources

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