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Proceedings of the 25th ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming, 2020
Data movement has a significant impact on program performance. For multithread programs, this impact is amplified, since different threads often interfere with each other by competing for shared cache space. However, recent de facto locality metrics consider either sequential execution only, or derive locality for multithread programs in an inefficient
Fangzhou Liu, Dong Chen, Wesley Smith, Chen Ding   +3 more
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ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies

Pathogens, 2023
African swine fever (ASF) is an important disease in swine currently producing a pandemic affecting pig production worldwide. Except in Vietnam, where two vaccines were recently approved for controlled use in the field, no vaccine is commercially ...
Manuel V. Borca, Elizabeth Ramirez-Medina, Ediane Silva, Ayushi Rai, Nallely Espinoza, Lauro Velazquez-Salinas, Douglas P. Gladue   +6 more
doaj   +1 more source

ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine

Viruses, 2022
African swine fever virus (ASFV) is the etiological agent of a swine pandemic affecting a large geographical area extending from Central Europe to Asia. The viral disease was also recently identified in the Dominican Republic and Haiti.
Elizabeth Ramirez-Medina, Elizabeth Vuono, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Alyssa Valladares, Edward Spinard, Ediane Silva, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +10 more
doaj   +1 more source

Full genome sequence for the African swine fever virus outbreak in the Dominican Republic in 1980

Scientific Reports, 2023
African swine fever is a lethal disease of domestic pigs, geographically expanding as a pandemic, that is affecting countries across Eurasia and severely damaging their swine production industry.
Edward Spinard, Vivian O’Donnell, Elizabeth Vuono, Ayushi Rai, Charronne Davis, Elizabeth Ramirez-Medina, Nallely Espinoza, Alyssa Valladares, Manuel V. Borca, Douglas P. Gladue   +9 more
doaj   +1 more source

The Presence of Virus Neutralizing Antibodies Is Highly Associated with Protection against Virulent Challenge in Domestic Pigs Immunized with ASFV live Attenuated Vaccine Candidates

Pathogens, 2022
African swine fever virus (ASFV) is currently producing a pandemic affecting a large area of Eurasia, and more recently, the Dominican Republic in the Western Hemisphere.
Ediane B. Silva, Peter W. Krug, Elizabeth Ramirez-Medina, Alyssa Valladares, Ayushi Rai, Nallely Espinoza, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine

Viruses, 2023
African swine fever (ASF) is a highly contagious disease that affects wild and domestic swine. Currently, the disease is present as a pandemic affecting pork production in Eurasia and the Caribbean region.
Elizabeth Ramirez-Medina, Ayushi Rai, Nallely Espinoza, Alyssa Valladares, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca, Douglas P. Gladue   +7 more
doaj   +1 more source

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene

Viruses, 2020
The African swine fever (ASF) pandemic is currently affecting pigs throughout Eurasia, resulting in significant swine production losses. The causative agent, ASF virus (ASFV), is a large, structurally complex virus with a genome encoding more than 160 ...
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ayushi Rai, Sarah Pruitt, Ediane Silva, Lauro Velazquez-Salinas, James Zhu, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +1 more source

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever

Viruses, 2021
The African swine fever virus (ASFV) is currently causing a pandemic affecting wild and domestic swine from Western Europe to Asia. No commercial vaccines are available to prevent African swine fever (ASF), resulting in overwhelming economic losses to ...
Manuel V. Borca, Elizabeth Ramirez-Medina, Ediane Silva, Elizabeth Vuono, Ayushi Rai, Sarah Pruitt, Nallely Espinoza, Lauro Velazquez-Salinas, Cyril G. Gay, Douglas P. Gladue   +9 more
doaj   +1 more source

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine

Viruses, 2020
E2 is the major structural glycoprotein of the classical swine fever virus (CSFV). E2 has been shown to be involved in important virus functions such as replication and virulence in swine.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Paul Azzinaro, Keith A. Berggren, Ayushi Rai, Sarah Pruitt, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca, Douglas P. Gladue   +9 more
doaj   +1 more source

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

Viruses, 2022
African swine fever virus (ASFV) causes a lethal disease (ASF) in domestic pigs, African swine fever (ASF). ASF is currently producing a pandemic affecting pig production across Eurasia, leading to a shortage of food accessibility.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Edward Spinard, Alyssa Valladares, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca, Douglas P. Gladue   +10 more
doaj   +1 more source