Results 1 to 10 of about 23,136 (263)

Live-attenuated foot-and-mouth disease virus vaccine engineered by codon deoptimization induces a strong protective immune response in cattle

npj Vaccines
Foot-and-mouth disease (FMD) is a fast-spreading, economically devastating veterinary viral disease. While inactivated vaccines have contributed to FMD control worldwide, recent outbreaks in Europe and Asia highlight the need for new control strategies ...
Sarah E. Attreed, Christina Silva, Monica Rodriguez-Calzada, Ryan D. Heimroth, Michael Oldakowski, Carolina Stenfeldt, Paul Azzinaro, Edward Spinard, Aishwarya Mogulothu, Steffen Mueller, Bruce Taillon, Jonathan Arzt, Elizabeth Rieder, Teresa de los Santos, Fayna Díaz-San Segundo, Gisselle N. Medina   +15 more
doaj   +1 more source

The Interaction between the DOCK7 Protein and the E2 Protein of  Classical Swine Fever Virus Is Not Involved with Viral Replication or Pathogenicity

Viruses, 2023
The classical swine fever virus (CSFV) particle consists of three glycoproteins, all of which have been shown to be important proteins involved in many virus functions, including interaction with several host proteins. One of these proteins, E2, has been
Elizabeth Vuono, Elizabeth Ramirez-Medina, Ediane Silva, Keith Berggren, Ayushi Rai, Nallely Espinoza, Manuel V. Borca, Douglas P. Gladue   +7 more
doaj   +1 more source

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

Viruses, 2021
African swine fever virus (ASFV) causes a devastating disease of swine that has caused outbreaks in Central Europe since 2007, spreading into Asia in 2018.
Elizabeth A. Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Nallely Espinoza, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source

EPIDEMIOLOGY OF PLUM POX VIRUS IN JAPANESE PLUMS IN SPAIN [PDF]

Acta Horticulturae, 2004
The Japanese plum (Prunus salicina) industry is economically important in Spain and in other countries with Mediterranean climate. P. salicina was described as a natural host of Plum pox virus (PPV) in Spain in 1984, where the ‘Red Beaut’ cultivar become an important source of inoculum and it spread the virus to apricots and plums along the Spanish ...
Cambra, Mariano, Gorris, María T., Capote, Nieves, Asensio, M., Martínez, M. Carmen, Bertolini, Edson, Collado, C., Hermoso-De-Mendoza, Alfonso, Mataix-Gato, Emilio, Lopez, A.   +9 more
openaire   +2 more sources

Contact Challenge of Cattle with Foot-and-Mouth Disease Virus Validates the Role of the Nasopharyngeal Epithelium as the Site of Primary and Persistent Infection

mSphere, 2018
The pathogenesis of foot-and-mouth disease virus (FMDV) in cattle was investigated through early and late stages of infection by use of an optimized experimental model for controlled contact exposure. Time-limited exposure of cattle to FMDV-infected pigs
Carolina Stenfeldt, Ethan J. Hartwig, George R. Smoliga, Rachel Palinski, Ediane B. Silva, Miranda R. Bertram, Ian H. Fish, Steven J. Pauszek, Jonathan Arzt   +8 more
doaj   +1 more source

Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish, Carolina Stenfeldt, Rachel M. Palinski, Steven J. Pauszek, Jonathan Arzt   +4 more
doaj   +1 more source

Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression

BMC Biotechnology, 2017
Background The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity.
Michael Puckette, Thomas Burrage, John G. Neilan, Max Rasmussen   +3 more
doaj   +1 more source

Association of the Host Immune Response with Protection Using a Live Attenuated African Swine Fever Virus Model

Viruses, 2016
African swine fever (ASF) is a lethal hemorrhagic disease of swine caused by a double-stranded DNA virus, ASF virus (ASFV). There is no vaccine to prevent the disease and current control measures are limited to culling and restricting animal movement ...
Jolene Carlson, Vivian O’Donnell, Marialexia Alfano, Lauro Velazquez Salinas, Lauren G. Holinka, Peter W. Krug, Douglas P. Gladue, Stephen Higgs, Manuel V. Borca   +8 more
doaj   +1 more source

Plums

Bulletin of popular information - Arnold Arboretum, Harvard University., 1918
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +4 more sources

Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum

Viruses, 2018
We have previously shown that Classical Swine Fever Virus (CSFV) p7 is an essential nonstructural protein with a viroporin activity, a critical function in the progression of virus infection. We also identified p7 domains and amino acid residues critical
Douglas P. Gladue, Eneko Largo, Lauren G. Holinka, Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Keith A. Berggren, Guillermo R. Risatti, Jose L. Nieva, Manuel V. Borca   +8 more
doaj   +1 more source