Results 131 to 140 of about 39,468 (302)

Fibrilpaint: A Class of Amyloid‐Targeting Peptides

Chemistry – A European Journal, EarlyView.
FibrilPaints are modular peptides engineered to recognize amyloid fibrils. By systematically varying charge, sequence, and termini, their binding behavior can be tuned while retaining recognition. Successful binding ″paints″ fibrils for visualization and opens routes toward targeted degradation and diagnostic applications.
Júlia Aragonès Pedrola, Françoise A. Dekker, Katrin Guttmann, Litske M. van Leeuwen, Shalini Singh, Guy Mayer, Tommaso Garfagnini, Assaf Friedler, Stefan G. D. Rüdiger   +8 more
wiley   +1 more source

Report on Wyandotte Pluronics [PDF]

Chemical & Engineering News Archive, 1954
openaire   +3 more sources

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Desenvolvimento de microesferas de diclofenaco de sódio de liberação prolongada: avaliação do potencial de utilização de blendas de acetobutirato de celulose e polaxamers na modulação do perfil de liberação do fármaco [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaO diclofenaco de sódio (DFS) é um antiinflamatório não-esteroidal (AINE), empregado para aliviar a dor e o desconforto ...
Medeiros, Daniela Cristina de
core  

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

Cytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Extracellular vesicles derived from edible plants and edible fungi: Compositional characteristics, engineering strategies and biofunctions

Food Biomacromolecules, EarlyView.
Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu, Rongheng Chen, Yuxuan Liu, Yizhen Xie, Fangyu Fan, Simin Feng, Ping Shao   +6 more
wiley   +1 more source

Carboxylic Acid- and Amine-Modified Pluronic F127-Based Thermoresponsive Nanogels as Smart Carriers for Brain Drug Delivery [PDF]

Abegaz Tizazu Andrgie,1 Cheng-Han Liao,2 Tsung-Yun Wu,2,3 Hsueh-Hui Yang,4 Horng-Jyh Harn,5,6 Shinn-Zong Lin,5,7 Yu-Shuan Chen,4,5,8 Hsieh-Chih Tsai2,3,9 1Department of Biotechnology, Debre Berhan University, Debre Berhan, Ethiopia; 2Graduate Institute ...
Yang HH, Harn HJ, Chen YS, Wu TY, Andrgie AT, Liao CH, Tsai HC, Lin SZ   +7 more
core  

Subchronic Exposure to Cannabis‐Based Nanoemulsions Induces Histopathological and Molecular Alterations in the Rat Submandibular Gland

Journal of Applied Toxicology, EarlyView.
ABSTRACT The increasing therapeutic incorporation of cannabis has expanded phytocannabinoid application, yet peripheral adverse effects like xerostomia raise concerns regarding emerging biotechnological formulations. This study evaluated the effects of cannabis‐based lipid nanoemulsions on the rat submandibular gland parenchyma.
Lorrany Avanci Bullo, Gabriel Carvalhal de Aguiar, Daniel Vitor Souza, Barbara dos Anjos Rosário, Flavia de Oliveira, Fernando Augusto Cintra Magalhaes, Nágila Maria Pontes Silva Ricardo, Edilberto Rocha Silveira, Dávila Zampieri, Milena de Barros Viana, Daniel Araki Ribeiro   +10 more
wiley   +1 more source

Leuco crystal violet-Pluronic F-127 3D radiochromic gel dosimeter

, 2019
This work reports results related to the manufacturing and optimisation of a leuco crystal violet (LCV)-Pluronic F-127 radiochromic gel dosimeter suitable for 3D radiotherapy dosimetry. A feature of this gel is that the natural gelatine polymer, which is
Kadlubowski, S., Jaszczak, M., Dudek, M., Papagiannis, P., Kouvati, K., Maras, P., Wach, R., Kozicki, M.   +7 more
core   +1 more source