Tailoring the Design of Dendritic Thermogels Through Carbosilane and Polyglycerol Crosslinkers. [PDF]
Recio-Ruiz J +4 more
europepmc +1 more source
Printed pluronic-based scaffolds : an attractive concept towards tissue regeneration [PDF]
Cornelissen, Maria +4 more
core +1 more source
Engineering positively charged alternating gyroid nanochannels in block copolymer membranes provides a powerful tool for efficient PFAS removal. ABSTRACT Ion‐exchange resins (IERs) can effectively remove per‐ and polyfluorinated alkyl substances (PFAS) from water through electrostatic interactions between the negatively charged PFAS and the positively ...
Séléane Murillon +10 more
wiley +1 more source
A Microwell Array Embedded Microfluidic Gradient Platform for Drug Screening on Tumor Spheroids
A microfluidic gradient platform embedded with high‐density microwell arrays (MEG platform) enables high‐throughput generation of uniform tumor spheroids for gradient‐based drug response assessment under dynamic perfusion. As a proof of concept, monoculture breast cancer cell (MCF‐7) spheroids and MCF‐7/human dermal fibroblast (HDF) co‐culture ...
Ling Liu, Guoying Wang, Ming Li
wiley +1 more source
Thermogelation of polymer nanoassemblies: promising platforms for injectable biomaterials in medical applications. [PDF]
Han B, van der Vlies AJ, Hasegawa U.
europepmc +1 more source
Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan +3 more
wiley +1 more source
Pirfenidone Reduces Intracochlear Fibrosis Caused by Cochlear Implantation in a Guinea Pig Model. [PDF]
Braack KJ +8 more
europepmc +1 more source
Hypersensitivity to Excipients in Drugs: An EAACI Position Paper
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey +10 more
wiley +1 more source
Design and Optimization of Thermosensitive Hydrogels Combined with Lipid Nanotechnology for Topical Curcumin Application. [PDF]
Vergara D +5 more
europepmc +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source

