Results 161 to 170 of about 39,468 (302)

Multi‐Scale 3D Printing of Magnetic Polymer Nanocomposites with Controlled Particle Dispersion and Hyperthermic Response

Small, EarlyView.
Dispersion of magnetic nanoflowers in trimethylolpropane ethoxylate triacrylate to generate photocurable nanocomposites is described. Particle dispersion provides processability and target AC‐field stimulated temperature increases. Complex (DLP) printed structures with submicron features are demonstrated, and the potential for stimulated release of ...
Eoin P. McKiernan, Jacek K. Wychowaniec, Danielle Winning, Shane Clerkin, Ines Martinez‐‐Chauvin, John Crean, Alexa Ennis, Colm Delaney, Larisa Florea, Dermot F. Brougham   +9 more
wiley   +1 more source

Programmable Porosity in Polymers via Microfluidic Templating and 3D Printing

Small Methods, EarlyView.
Fluid templating is a powerful way to produce porous polymers. Microfluidic technologies enable fine control over the dimension and packing of bubbles and droplets. Combined with additive manufacturing, microfluidic templating enables the creation of polymeric functionally graded porous materials in which both porosity and three‐dimensional geometry ...
Federico Serpe, Roberta Angelini, Andrea Barbetta, Vanessa Rosciardi   +3 more
wiley   +1 more source

Wearable OLED-Assisted Photodynamic Cancer Therapy Using Chlorin e6-Loaded Pluronic Nanocapsules as Photosensitizers. [PDF]

Adv Healthc Mater
Oh H, Jeong SM, Park CH, Son P, Lee Y, Koo H, Choi WI, Choi KC.   +7 more
europepmc   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Photophysical Properties of Coumarin 343 and Structural Changes in Reline-Pluronic Systems With Varying Block Composition. [PDF]

Chem Asian J
Sinha S, Srivastava S, Aswal VK, Seth D.
europepmc   +1 more source

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Green Chemistry Oriented Pluronic F127/Carbopol Nanogel Platform (NGLp) Encapsulating <i>Lippia pedunculosa</i> Essential Oil for <i>Aedes aegypti</i> Larval Control. [PDF]

ACS Omega
Andrade LGS, de Sousa JDS, Nojosa ECN, da Silva Santos AM, Pires Souza M, Marques Brandão C, Holanda CA, da Silva Filho EC, Osajima JA, Menezes LRA, Costa EV, Gonçalves RS.   +11 more
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

From Porphyrins to Versatile Photostable Bacteriochlorins: Triplet-State-Driven Design of Perfluorinated Photosensitizers. [PDF]

J Med Chem
Barczyk D, Warszyńska M, Repetowski P, Kuncewicz J, Dąbrowski JM.   +4 more
europepmc   +1 more source

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes, Toniana G. Carvalho, Luan A. Pereira, Emanuele G. Silva, Esther M. A. Maciel, Gabriella P. Torres, Thiago Assis, Pablo L. Cardozo, Joao P. P. de Almeida, Nathalia C. Silva, Francesca Pischedda, Giovanni Piccoli, Luciene B. Vieira, Juliana Alves‐Silva, Fabiola M. Ribeiro   +14 more
wiley   +1 more source