Results 171 to 180 of about 39,468 (302)

New Expanded Pluronic Grid [PDF]

Chemical & Engineering News Archive, 1962
openaire   +3 more sources

Uniform Microscale Thermoresponsive Liposomes for Controlled Release Above Body Temperature. [PDF]

Small
Mousavi SM, Zhang Y, Pandzic E, Inglis DW, Lord MS, Taylor RA, Li M.   +6 more
europepmc   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

Two-Dimensional UVA Dose Mapping Using a TTC-Pluronic F-127 Hydrogel Dosimeter. [PDF]

Materials (Basel)
Sąsiadek-Andrzejczak E, Kozicki M.
europepmc   +1 more source

HAVE YOU PIGEONHOLED THE PLURONICS? [PDF]

Chemical & Engineering News Archive, 1957
openaire   +1 more source

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro, Lucía Martín‐Banderas, Josefa Álvarez‐Fuentes, María Dolores Herrera‐González   +3 more
wiley   +1 more source

Graphene and Graphene Oxide-Based Nanocarriers for Targeted Delivery of Mitoxantrone in Cancer Therapy. [PDF]

Int J Nanomedicine
Talebi Haftadori Z, Mahdavian L, Mirjafary Z, Ghorbani SH.   +3 more
europepmc   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Targeted, receptor‐mediated delivery of a masked d‐amino acid cell‐penetrating peptide for cell‐specific phototoxicity

The FEBS Journal, EarlyView.
A targeted phototoxic peptide selectively accumulates in cells expressing chemokine‐like receptor 1 (CMKLR1). Phototoxicity of the native peptide is low, but cleavage by lysosomal protease cathepsin B releases a 6‐tetramethylrhodamine (TMR) labeled nona‐ᴅ‐arginine which mediates lysosomal rupture and cell death upon irradiation.
Moritz List, Eva‐Maria Jülke, Annette G. Beck‐Sickinger   +2 more
wiley   +1 more source

Injectable Thermoresponsive Hydrogels for Localized Drug Delivery: Mechanisms, In Vivo Evidence and Translational Challenges. [PDF]

J Funct Biomater
Di Martino M, Sessa L, Pagliari G, Silvestrino D, Concilio S.   +4 more
europepmc   +1 more source