Results 101 to 110 of about 15,930 (228)

The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects

open access: yesTherapeutic Advances in Neurological Disorders, 2016
B cells play a central role in the pathogenesis in multiple sclerosis (MS), being involved in the activation of proinflammatory T cells, secretion of proinflammatory cytokines, and production of autoantibodies directed against myelin. Hence, the usage of
Per Soelberg Sorensen   +1 more
doaj   +1 more source

Rigorous Electromagnetic Quasinormal‐Mode Method Made Easy for Users

open access: yesLaser &Photonics Reviews, EarlyView.
We present a method that combines numerical techniques with accurate approximations to enable simple and ultrafast computations of the scattered field based on quasinormal modes expansions. The method is made available in the open‐source package MANlite implemented within COMSOL.
Tong Wu, Philippe Lalanne
wiley   +1 more source

A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus.

open access: yesPLoS ONE, 2019
Systemic lupus erythematosus (SLE) is a chronic, remitting, and relapsing, inflammatory disease involving multiple organs, which exhibits abnormalities of both the innate and adaptive immune responses.
Yupeng Li   +10 more
doaj   +1 more source

Responsive Phase Gradient Metasurface for Laser Stealth and Dynamic Thermal Camouflage

open access: yesLaser &Photonics Reviews, EarlyView.
The graphical abstract depicts a phase‐gradient metasurface enabling directional scattering and emissivity‐controlled thermal radiation. The engineered phase profile redistributes the reflected optical momentum, suppressing specular reflection and generating non‐specular scattering.
Zhihao Yuan   +7 more
wiley   +1 more source

Regulation of ErbB4 signaling by post-translational modifications [PDF]

open access: yes, 2017
ErbB4 is a member of the epidermal growth receptor family (EGFR/ErbB1, ErbB2, ErbB3, ErbB4) of receptor tyrosine kinases. ErbB receptors are activated by extracellular growth factor ligands, and control the activity of intracellular signaling ...
Knittle, Anna M.
core  

Fluorescent Supramolecular Gels Based on D‐Sorbitol Derivatives

open access: yesSmall, EarlyView.
Sugar‐based fluorescent low‐molecular‐weight gelators (LMWGs) DNapS, DBTDS, and MCumS, prepared by a green, scalable route, form supramolecular gels in water, organic, and deep eutectic solvents. MCumS yields solvent‐dependent nanofibrous networks and viscoelastic injectable eutectogels.
Emmanuel Odella   +5 more
wiley   +1 more source

Role jaderných tělísek PML ve vrozené imunitní odpovědi během virové infekce [PDF]

open access: yes
The aim of this thesis is to summarize the findings on the involvement of PML nuclear bodies in the regulation of the innate immune response. The thesis includes a description of PML nuclear bodies and the immune response to viral infection. It describes
Mališová, Pavla
core  

Quasi‐BIC and Reflective Mode Coupling Drives SHG Beyond the Q Factor Limit

open access: yesSmall, EarlyView.
An analytical expression is developed to relate second‐harmonic generation to both the resonance Q factor and absorptance. Simulations and experiments on a dual‐resonance 3R‐MoS2 metasurface validate the formula, showing that absorptance engineering provides an effective route to enhance SHG beyond conventional Q‐only design.
Wenkai Yang   +8 more
wiley   +1 more source

Intracellular restriction factors of small DNA viruses [PDF]

open access: yes, 2019
Tématem této práce je shrnutí poznatků o proteinových restrikčních faktorech, které se uplatňují v infikovaných buňkách při infekci malými viry s DNA genomem čeledí Hepadnaviridae, Parvoviridae, Polyomaviridae a Papillomaviridae.
Anderová, Karolína
core  

Robust Partial Multi‐Label Learning Under Dual Noise via Joint Subspace Learning

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Partial Multi‐label Learning (PML) deals with the ambiguity where each instance is annotated with a set of candidate labels, and only a subset of which is valid. While existing PML methods focus primarily on label disambiguation, they often rely on the assumption of a clean feature space.
Yuanjian Zhang   +4 more
wiley   +1 more source

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