Results 81 to 90 of about 15,930 (228)

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

lnstructions to the Weak and the Strong According to Romans 14 [PDF]

, 1950
Eternal vigilance is the price of Christian liberty which was restored to Christendom through the Lutheran Reformation. Legalism and license always have been and still are the implacable foes of Christian liberty and ultimately of the Gospel itself ...
Gaertner, C. A.
core   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Monocyte maturation pattern by flow cytometry expression of CD64, CD300e, and CD14 correlates to presence of myeloid neoplasm and helps identify blast equivalents in the setting of monocytic neoplasm

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD300e is a marker of mature monocytes in flow cytometry; however, there is limited detailed information on staining patterns in conjunction with other monocyte markers. We evaluated the flow cytometric staining patterns of CD64, CD14, and CD300e in 12 negative and 33 positive peripheral blood specimens and 16 negative and 56 positive bone ...
Jenny Zhang, Jacob Kaplan, Elizabeth Courville   +2 more
wiley   +1 more source

Analysen zur Assemblierung von Centromeren und PML-Kernkörperchen in lebenden Zellen [PDF]

, 2007
Essenzielle Funktionen im eukaryotischen Zellkern wie RNA-Transkription, DNA-Replikation und DNA-Reparatur werden von makromolekularen Proteinkomplexen bewerkstelligt.
Weidtkamp-Peters, Stefanie
core  

Safeguarding Online Research in Eating Disorders Against Fraud: Increasing Risks and Practical Recommendations

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Recent growth of online research has been accompanied by an increase in reports of fraudulent participants, which can significantly comprise research validity. Drawing from our experience using Qualtrics with open recruitment, existing literature, and emerging studies in eating disorders (ED), we outline the risk and provide simple ...
Jamie‐Lee Pennesi, Mia L. Pellizzer, Tracey D. Wade   +2 more
wiley   +1 more source

Development and Validation of the Body Neutrality Questionnaire

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Body neutrality has emerged as an alternative framework within the positive body image literature. This study developed the Body Neutrality Questionnaire (BNQ), the first validated measure of body neutrality for young adults. Method An initial item pool was developed using expert consultation and focus group review.
Amelia Kimpton, Laura Edney, Charles Goya, Tracey D. Wade, Mia L. Pellizzer   +4 more
wiley   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

Promyelocytic leukaemia protein isoform II and mild heat stress compromise human adenovirus type 5 gene expression [PDF]

Promyelocytic Leukaemia proteins (PML), the core component of PML nuclear bodies (NB), are implicated in many critical cellular functions. One of those is confronting virus infection: DNA and RNA viruses target PML-NB and interact with PML proteins and ...
Atwan, Zeenah
core  

Alternative splicing : the pledge, the turn, and the prestige : the key role of alternative splicing in human biological systems [PDF]

, 2017
© The Author(s) 2017. This article is an open access publication. Open Access. This article is distributed under the terms of the Crea-tive Commons Attribution 4.0 International License (http://crea-tivecommons.org/licenses/by/4.0/), which ...
Ascensão-Ferreira, Mariana, Barbosa-Morais, Nuno, Bordone, Marie C., Gallego Páez, Lina Marcela, Leote, Ana Carolina, Saraiva-Agostinho, Nuno   +5 more
core   +2 more sources