Telomere dynamics in ectotherms remain poorly understood relative to endotherms, yet are increasingly relevant in the context of climate change. Here, we used model‐averaged GLMMs and hierarchical partitioning to disentangle intrinsic and extrinsic drivers of relative telomere length in the Western‐Canaries Lizard (Gallotia galloti) across a 10‐year ...
Edward Gilbert +9 more
wiley +1 more source
Progressive Multifocal Leukoencephalopathy in a Patient With Miliary Tuberculosis: Differential Diagnosis From Tuberculoma. [PDF]
Baek JG, Kwon HJ, Chae HM, Kwon DH.
europepmc +1 more source
Unfavourable H‐CDR3 Loops in preB Cells Lead to Highly Expanded Plasma Cell Clones
In the absence of a pre‐BCR, a subset of mature B cells that expresses IgH chains with very short, hydrophobic and positively charged H‐CDR3 loops is generated. This results in massive clonal expansion and the development of autoreactive plasma cells exhibiting these characteristics.
Alaitz Aranburu +7 more
wiley +1 more source
Atypical single <i>PML</i>::<i>RARA</i> fusion in acute promyelocytic leukemia: mechanisms and clinical implications. [PDF]
Yang P +9 more
europepmc +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
This review highlights how nanomaterials with high adsorption capacities including carbon‐based structures, transition metal oxides, 2D layers, and zeolites enable sensitive and selective detection of toxic gases and VOCs. Their tailored properties and sensing mechanisms drive the development of next‐generation gas sensors for environmental and ...
Hamdy A. Ismail +9 more
wiley +1 more source
The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi +5 more
wiley +2 more sources
Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeres. [PDF]
Taylor ER +11 more
europepmc +1 more source
National and Subnational Models of Care That Support Primary Health Care: A Mixed‐Methods Study
ABSTRACT In 2020, the World Health Assembly called on countries to reorient their models of care (MOCs) toward primary health care (PHC). This study's objectives were to (a) describe common use of the concept of MOC; and (b) identify implemented MOCs and their components that support PHC at national and subnational levels. A scoping review charted data
Mary Louisa Plummer +5 more
wiley +1 more source
Asciminib and pulsed ATRA as post-remission therapy in T315I mutated PML-RARA-positive blast crisis of chronic myeloid leukemia. [PDF]
Mazzarella R +17 more
europepmc +1 more source

