Results 181 to 190 of about 36,450 (302)

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni, Maria Luisa Di Paolo, Antonio Laghezza, Giorgio Cozza, Francesco Piazzola, Laura Facci, Emma Marcolin, Elena Roggiolani, Luca Piemontese, Anna Minarini, Morena Zusso, Lisa Dalla Via, Michela Rosini   +12 more
wiley   +1 more source

Acute promyelocytic leukaemia presenting with gingival hypertrophy: an atypical oral presentation. [PDF]

Oxf Med Case Reports
Antiri EK, Ekem IAE.
europepmc   +1 more source

End‐to‐End Deep Learning Framework for Freeform Metasurfaces via Non‐Uniform Rational B‐Splines Meta‐Atoms

Nanophotonics, Volume 15, Issue 15, 13 August 2026.
This work presents a NURBS‐enabled metasurface design framework that combines freeform meta‐atom parameterization with Transformer‐based deep learning. The unified mathematical representation expands geometric degrees of freedom while enabling efficient optical‐response prediction and inverse design.
Kaipeng Liu, Junliang Jia, Kun Li, Yuanjian Wan, Runlin Zhou, Xuyang Chen, Chao Wang, Zhixiang Huang, Jiaxin Li, Gang Gao, Pei Zhang, Longqiu Li   +11 more
wiley   +1 more source

Clinical implications of natalizumab Fab-arm exchange in patients with multiple sclerosis. [PDF]

Front Immunol
Gelissen LMY, van den Berg SPH, Toorop AA, Wijburg MT, Tallantyre EC, Derksen NIL, Loeff FC, Killestein J, Rispens T, van Kempen ZLE, NEXT-MS study group .   +10 more
europepmc   +1 more source

Broadband Electromagnetic Field Prediction at Unseen Wavelengths via Physics‐Guided Neural Operators

Nanophotonics, Volume 15, Issue 15, 13 August 2026.
A physics‐guided neural operator is trained on electromagnetic field distributions at discrete wavelengths across diverse nanophotonic structures. At inference, given any permittivity map and query wavelength, the model predicts continuous broadband electric‐field distributions with full‐wave accuracy, including wavelengths unseen during training ...
Joonhyuk Seo, Chanik Kang, Dongjin Seo, Haejun Chung   +3 more
wiley   +1 more source

Resolution of PML after Treatment with Virus-Specific T Cells and HCT. [PDF]

N Engl J Med
Gonzalez CE, Fletcher A, Jenkins TL, Zahraeifard S, Peterson R, Taylor M, Jones C, Urban A, Avila D, Campillay M, Wilhelm J, Soldatos A, Kuhle J, Jain P, Corey S, Bergerson JRE, Reich DS, Highfill S, Stroncek D, Dinh A, Pittaluga S, Kong HH, Su HC, Notarangelo LD, Pai SY, Grimley M, Freeman AF, Cortese I.   +27 more
europepmc   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Successful Mitral Valve Repair for Single Leaflet Device Attachment Following Transcatheter Edge-to-Edge Repair: A Case Report. [PDF]

Case Rep Cardiol
Makiura T, Daimon M, Katsumata T.
europepmc   +1 more source

A Hybrid Computational Framework for PCF‐based SPR Sensor With Machine Learning and xAI

Advanced Materials Interfaces, Volume 13, Issue 15, 4 August 2026.
A photonic crystal fiber‐based surface plasmon resonance (SPR) sensor integrating rectangular air holes along with conventional circular air holes achieves exceptional wavelength sensitivity of 15,000 nm/RIU across a broad refractive index range of 1.31–1.39. Integrated machine learning with explainable AI (xAI) models achieves high prediction accuracy
Mahabur Rahman Fahim, Sudeep Paul, Musrat Jahan, Md Abu Shahid Chowdhury   +3 more
wiley   +1 more source