Results 201 to 210 of about 36,450 (302)

Nuclear PML expression as a prognostic biomarker in localised clear cell renal cell carcinoma

BJUI Compass, Volume 7, Issue 8, August 2026.
Abstract Objectives To evaluate nuclear promyelocytic leukaemia protein (PML) expression as a prognostic biomarker in localised clear cell renal cell carcinoma (ccRCC), aiming to improve postoperative risk stratification. Materials and methods Two independent retrospective cohorts of patients undergoing surgery for localised ccRCC were analysed: an ...
Sakari Kosola, Teemu D. Laajala, Iida Payne, Antti Kukkula, Lassi Luomala, Tuomas Mirtti, Kalle Mattila, Paula Vainio, Maria Sundvall, Panu M. Jaakkola   +9 more
wiley   +1 more source

Parenting styles and freshman's internet gaming disorder: a moderated chain mediation model involving presence of meaning in life and self-control. [PDF]

Front Psychol
Jia H, Zhang Y, Obaid A, Sulaiman F, Zhu H.   +4 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Progressive Multifocal Leukoencephalopathy in AIDS: The Diagnostic Role of PET Imaging. [PDF]

Infect Dis Rep
Donini V, Paggi R, Farese A, Malcontenti C, Tagliaferri E, Caroselli C, Sani S, Matteini M, Bartoloni A, Zammarchi L.   +9 more
europepmc   +1 more source

IL‐6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA‐Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Purpose To investigate the expression profile of IL‐6 in patients with acute promyelocytic leukemia (APL) and its role in modulating the ability of hPMSCs to regulate the differentiation of NB4 cells. Methods Peripheral blood samples were obtained from newly diagnosed APL patients and healthy controls.
Rong Qi, Hengchao Zhang, Yunhua Wu, Yanchao Ma, Xiying Luan   +4 more
wiley   +1 more source

A novel <i>PML::RARA</i> fusion in acute promyelocytic leukemia: a case report and literature review. [PDF]

Front Oncol
Chen JP, Hou JJ, Chen XY, Cao YX, Ke P, Zhou JH, Hu LN.   +6 more
europepmc   +1 more source

Improvement in Outcomes of Childhood Acute Myeloid Leukemia Treatment: A Survival Analysis at a Reference University Hospital in Rio de Janeiro, Brazil

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Acute myeloid leukemia (AML) represents 15% to 20% of all pediatric acute leukemias and is responsible for nearly 30% of deaths in this population. While high‐income countries report overall survival (OS) rates near 75%, survival in Brazil remains significantly lower, ranging between 30% and 40%.
Thais Alcantara Bonilha, Deborah Sutter Ayres Pereira, Alice Maria Boulhosa de Azevedo, Adriana Martins de Sousa, Elaine Sobral da Costa, Marcelo Gerardin Poirot Land   +5 more
wiley   +1 more source

Pembrolizumab Experience in a Patient with Progressive Multifocal Leukoencephalopathy Following Multiple Myeloma Treatment: A Case Report and Literature Review. [PDF]

Noro Psikiyatr Ars
Yıldız MS, Maharramov E, Yıldız FG, Tan E, Özen NPA, Göçmen R, Tuncer A.   +6 more
europepmc   +1 more source

Bard1‐Mediated Regulation of Hnrnpa2b1 Ubiquitination and Protein Stability Contributes to Neuronal Ferroptosis and Cognitive Dysfunction Following Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Bard1‐mediated ubiquitination of Hnrnpa2b1 in mice with PSCI destabilizes Sptbn2, which prevents the membrane translocation of Slc7a11 and reduces cystine uptake. This disruption of antioxidant defense triggers ferroptosis in hippocampal neurons, highlighting a novel molecular pathway linking post‐stroke cognitive impairment to ferroptosis of ...
Tuming Li, Tianyi Rong, Zuoting Shen, Zhenyu Wei, Deyan Chen, Ping Zhong, Li Cao   +6 more
wiley   +1 more source

Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis. [PDF]

J Clin Invest
Gan C, Lai E, Tai Y, Chen S, Zhao C, Dai W, Yang Z, Li B, Lan T, Xiao Y, Guo Y, Chen J, Wei B, Che Z, Cao S, Liu M, Tacke F, Tang C, Shah VH, Yu H, Wang F, Huang Z, Gao J.   +22 more
europepmc   +1 more source