Results 211 to 220 of about 42,451 (299)

Primary Extramedullary Acute Promyelocytic Leukemia Presenting as Cauda Equina Syndrome: A Rare Case Report and Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT APL presenting as an extramedullary mass is exceedingly rare. Here, we describe extramedullary APL causing cauda equina syndrome, underscoring the diagnostic challenges associated with an atypical presentation, highlighting the complexity of distinguishing extramedullary APL from other conditions, and discussing the stepwise approach to ...
Amir Ali   +8 more
wiley   +1 more source

Qingdainone, a novel bioactive compound in Realgar‒Indigo naturalis, induced apoptosis and differentiation in ATRA‐sensitive and ‐resistant acute promyelocytic leukaemia cells

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
1. Network pharmacology identified Qingdainone as a key bioactive compound in RIF. 2. Molecular docking revealed strong binding affinities of Qingdainone to targets such as CCND1, CDK1, CDK4, CASP3 and CASP7. 3. Qingdainone interfered proliferation and apoptosis, and promoted differentiation, of ATRA‐sensitive and ‐resistant APL cells, such that ...
Pengcheng Xu   +7 more
wiley   +1 more source

Multiple Scattering Suppression in Heterogeneous Media: High‐Precision Imaging of Sleeve Grouting Defects Based on Elastic Reverse Time Migration

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
This study proposes an elastic wave reverse time migration (RTM) method to suppress multiple scattering noise in heterogeneous concrete. By effectively utilizing scattered wavefields, RTM enables high‐precision, robust imaging of sleeve grouting defects in prefabricated buildings, significantly outperforming traditional algorithms.
Yong Lu, Li Tian, Sheng Yuan, Jing Zhang
wiley   +1 more source

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