Differentiation therapy in acute myeloid leukaemia: molecular basis, clinical progress, and future perspectives. [PDF]
Asiri A.
europepmc +1 more source
Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia
Peroxisomes are emerging as key regulators of lipid metabolism in leukemia. Enhanced metabolism of very‐long‐chain fatty acids (VLCFAs) supports leukemia cell survival, redox homeostasis, and therapeutic resistance. Pharmacologic disruption of peroxisomal fatty acid oxidation causes VLCFA accumulation, oxidative stress, and mitochondrial dysfunction ...
Ekaterina N. Parfenova +1 more
wiley +1 more source
Atypical single <i>PML</i>::<i>RARA</i> fusion in acute promyelocytic leukemia: mechanisms and clinical implications. [PDF]
Yang P +9 more
europepmc +1 more source
Ribosomal Proteins in Cell Biology and Cancer
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang +4 more
wiley +1 more source
Progressive Multifocal Leukoencephalopathy in a Patient With Miliary Tuberculosis: Differential Diagnosis From Tuberculoma. [PDF]
Baek JG, Kwon HJ, Chae HM, Kwon DH.
europepmc +1 more source
Quasi‐BIC and Reflective Mode Coupling Drives SHG Beyond the Q Factor Limit
An analytical expression is developed to relate second‐harmonic generation to both the resonance Q factor and absorptance. Simulations and experiments on a dual‐resonance 3R‐MoS2 metasurface validate the formula, showing that absorptance engineering provides an effective route to enhance SHG beyond conventional Q‐only design.
Wenkai Yang +8 more
wiley +1 more source
Case report: <i>TTMV::RARA</i>-positive pediatric APL with spinal cord compression as initial presentation: unique clinical features and therapeutic outcomes revealed by a 12-case systematic cohort analysis. [PDF]
Yang HL +11 more
europepmc +1 more source
Abstract Understanding the genome‐wide diversity of jute mallow (Corchorus olitorius L.) is crucial for unlocking the potential of global genebank collections, enabling the discovery and use of traits that support climate resilience, improve nutrition, and increase productivity.
Abdul J. Shango +11 more
wiley +1 more source
In Situ Engineered "Cascade-Amplified" Drug-Loaded Vesicles for Enhanced Cancer Stem Cell Therapy. [PDF]
Zhang T +11 more
europepmc +1 more source
Home‐Based Versus In‐Hospital Care in Pediatrics: A Systematic Review of Cost‐Effectiveness Studies
ABSTRACT Home‐based care has emerged as a potential alternative to traditional hospital‐based care for children and adolescents worldwide. This systematic review aimed to systematically gather and critically assess the available evidence on the cost‐effectiveness of home‐based versus in‐hospital care for pediatric populations globally.
Luís Carlos Lopes‐Júnior +8 more
wiley +1 more source

