Comment on 'Systematic Review and Meta-Analysis of Protein Intake to Support Muscle Mass and Function in Healthy Adults' by Nunes et al.-The Authors' Reply. [PDF]
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
Nunes EA +6 more
europepmc +2 more sources
pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates in Portugal [PDF]
ABSTRACT The nucleotide sequences of the pncA genes within 55 multidrug-resistant pyrazinamide-resistant Mycobacterium tuberculosis clinical isolates were determined. Fifty-three out of the 55 isolates were pyrazinamidase (PZase) negative. Four strains contained a wild-type
Portugal, I +3 more
openaire +3 more sources
Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis [PDF]
ABSTRACT Thirty-four pyrazinamide-resistant and 37 pyrazinamide-susceptible Mycobacterium tuberculosis complex strains were analyzed for pncA gene mutations. None of the sensitive strains had any mutations, apart from silent mutations, whereas all but one resistant strain showed
Pontus, Juréen +3 more
openaire +2 more sources
Caecal digestibility as an approximation of ileal protein digestibility evaluation in rats
The rat model can be used to assess ileal protein digestibility rapidly and in first intention, but no standardised method exists. Our objective was to compare methods to assess protein digestibility, depending on collection site (ileum/caecum) and use ...
Florence M. Guillin +6 more
doaj +1 more source
Mutations associated with pyrazinamide resistance in pncA of Mycobacterium tuberculosis complex organisms [PDF]
A gene (pncA) with mutations associated with pyrazinamide resistance in Mycobacterium tuberculosis complex members was characterized in 67 pyrazinamide-resistant and 51 pyrazinamide-susceptible isolates recovered from diverse geographic localities and anatomic sites and typed by IS6110 profiling.
S, Sreevatsan +4 more
openaire +2 more sources
Gibbs Free Energy Calculation of Mutation in PncA and RpsA Associated With Pyrazinamide Resistance [PDF]
Une approche centrale pour mieux comprendre les forces impliquées dans le maintien des structures protéiques consiste à étudier le repliement des protéines et les propriétés thermodynamiques. L'effet du processus de pliage est souvent perturbé dans les états mutés.
Muhammad Tahir Khan +6 more
openaire +3 more sources
Although plant proteins are often considered to have less nutritional quality because of their suboptimal amino acid (AA) content, the wide variety of their sources, both conventional and emerging, suggests potential opportunities from complementarity ...
Laurianne Dimina +4 more
doaj +1 more source
LiNi0.8Co0.15Al0.05O2 (NCA) secondary particles with high tap density have a great potential for high volumetric energy density lithium (Li)‐ion power battery.
Cheng Liu +6 more
doaj +1 more source
Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA [PDF]
Pyrazinamide (PZA) is one of the three most important drugs for treatment of Mycobacterium tuberculosis infections. The antibacterial activity of PZA requires a bacterial enzyme, pyrazinamidase (PZAase), which hydrolyzes PZA to form pyrazinoic acid and ammonia. Most PZA-resistant clinical M. tuberculosis isolates lack PZAase activity.
R, Frothingham +4 more
openaire +2 more sources
Colorimetric methods for rapid determination of pyrazinamide resistance
Background: Because pyrazinamide (PZA) is only effective for Mycobacterium tuberculosis at an acidic pH, susceptibility tests are more difficult to perform than those for other anti-tuberculosis (TB) drugs.
Ahmet Ugur Akbal +2 more
doaj +1 more source

