pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates from Northwestern Russia [PDF]
Antimicrobial Agents and Chemotherapy, 1999 ABSTRACT Thirty-six pyrazinamide-resistant and eight pyrazinamide-susceptible Mycobacterium tuberculosis isolates from Russia were analyzed for their pncA mutations. Thirty-one (86.1%) of the resistant isolates had a mutation either in pncA or upstream of the
H J, Marttila +6 more
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Advanced Science, Volume 13, Issue 3, 14 January 2026.This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss +9 more
wiley +1 more source
A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings. [PDF]
PLoS ONE, 2016 In South Africa and other high prevalence countries, transmission is a significant contributor to rising rates of multidrug resistant tuberculosis (MDR-TB). Thus, there is a need to develop an early detection system for transmission clusters suitable for
Halima M Said +12 more
doaj +1 more source
Author Correction: Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis. [PDF]
, 2018 A correction to this article has been published and is linked from the HTML and PDF versions of this paper.
Ahmed, N +6 more
core +1 more source
VIEW, Volume 6, Issue 6, December 2025.Despite efficacious antiretroviral therapy, 10%–40% of HIV‐infected individuals exhibit inadequate immune reconstitution due to persistent inflammatory activation and NAD+ metabolic dysregulation—a critical cofactor in cellular bioenergetics. We administered silibinin to 53 HIV immunological non‐responders and elucidated its mechanism through selective
Wenli Liu +13 more
wiley +1 more source
Plant analysis as a tool to determine crop nitrogen status [PDF]
, 2007 An effective plant nutrient management strategy optimises nitrogen (N) use efficiency for minimised environmental impact, while ensuring an optimum N status of the crop for good product quality and maximum growth.
Ekbladh, Göran
core
CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis. [PDF]
, 2015 Tuberculosis kills more than a million people annually and presents increasingly high levels of resistance against current first line drugs. Structural information about Mycobacterium tuberculosis (Mtb) proteins is a valuable asset for the development of
Blundell, Tom L +2 more
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Antibiotic Resistance: A Genetic and Physiological Perspective
MedComm, Volume 6, Issue 11, November 2025.The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy +9 more
wiley +1 more source
Beyond the Nca: New Results for the Spectral Properties of the Anderson Model
, 1994 In the framework of direct perturbation theory a fully self-consistent approximation beyond the well known NCA will be presented for the Anderson Model. The resummation of a class of skeleton diagrams up to infinite order in $V$ includes all contribution
Bickers +5 more
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The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa [PDF]
, 2010 Background. The Beijing genotype of M. tuberculosis is a virulent strain that is disseminating worldwide and has a strong association with drug resistance.
A Aubry +77 more
core +4 more sources