Results 81 to 90 of about 5,852 (197)
Characterization ofpncAMutations of Pyrazinamide-ResistantMycobacterium tuberculosisin Korea [PDF]
Journal of Korean Medical Science, 2001 Pyrazinamide (PZA) is one of the most important drugs for the treatment of Mycobacterium tuberculosis infection. However, the increasing frequency of PZA-resistant strains limits its effectiveness. In Korea, most PZA-resistant strains also exhibit both isoniazid and rifampin resistance making it essential to identify these resistant strains accurately ...
K W, Lee, J M, Lee, K S, Jung
openaire +2 more sources
Informe de labores PNCA-1987 [PDF]
, 1988 96 páginasEste documento presenta las actividades de Labores del PNCA-1987, cursos, talleres, documentos, actividades institucionales y ...
Instituto Interamericano de Cooperación para la Agricultura (IICA) +2 more
core
ANALISIS MUTASI GEN pncA DAN STRUKTUR PROTEINNYA UNTUK MENGUNGKAP DASAR RESISTENSI PIRAZINAMID PADA ISOLAT KLINIS Mycobacterium tuberculosis [PDF]
, 2013 PZA adalah salah satu obat andalan yang direkomendasikan WHO untuk terapi TB. Munculnya resistensi PZA pada isolat-isolat klinis M. tuberculosis sering dihubungkan dengan terjadinya mutasi gen pncA penyandi PZase.
Purkan, 0016117201
core +3 more sources
ChemMedChem, Volume 20, Issue 18, September 25, 2025.(E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides with 2‐OH, 2,3‐diOH or 2,4‐diOH substitution exhibit good antimycobacterial or antiproliferative activity, and iron chelation similar to salicylaldehyde isonicotinoyl hydrazone (SIH). A series of 33 (E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides and their derivatives were synthesized and tested for biological ...
Priam‐Amedeo Houngbedji +14 more
wiley +1 more source
Exploring of pyrazinamidase recombinant activity from PZA-sensitive and resistant Mycobacterium tuberculosis expressed in Escherichia coli BL21 (DE3) [PDF]
Brazilian Journal of BiologyThe mutations of pncA gene encoding pyrazinamidase/PZase in Mycobacterium tuberculosis are often associated with pyrazinamide/PZA resistance. The H and R1 isolates showed significant phenotypic differences to PZA.
P. Purkan +9 more
doaj +1 more source
Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis
Advanced Science, Volume 12, Issue 32, August 28, 2025.Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard +13 more
wiley +1 more source
BMC Infectious Diseases, 2020 Background Pyrazinamide still may be a useful drug for treatment of rifampin-resistant (RR-TB) or multidrug-resistant tuberculosis (MDR-TB) in China while awaiting scale up of new drugs and regimens including bedaquiline and linezolid.
Hui Xia +6 more
doaj +1 more source
Inscriptions, 2022 What is it like, the event in which we become ourselves? What is its relationship to other kinds of event? And where might the event happen? When people say today that they “stand with” or that they are “allies,” they are challenging hierarchical notions
David Ritchie
doaj
The FASEB Journal, Volume 39, Issue 14, 31 July 2025.This research elucidates NAD+ biosynthesis in Streptococcus mutans, revealing reliance on the nicotinic acid salvage pathway and an incomplete PnuC–NadR route. SmNiaR, a nicotinic acid‐responsive transcriptional regulator, orchestrates the transcriptional regulation of this pathway.
Haojie Yu +8 more
wiley +1 more source
Six profiles of the applied forces along Direction 2 in AbPncA. [PDF]
, 2012 Six profiles of the applied forces along Direction 2 in AbPncA.
Qing-Chuan Zheng (107139) +3 more
core +1 more source