Results 81 to 90 of about 2,990 (173)

Pyrazinamide resistance associated with pncA gene mutation in Mycobacterium tuberculosis in Japan

Epidemiology and Infection, 2002
Thirty Japanese clinical isolates of Mycobacterium tuberculosis were analysed by pyrazinamide susceptibility testing and pyrazinamidase assay, as well as polymerase chain reaction for single-strand conformational polymorphism and direct sequencing of the gene encoding pyrazinamidase (pncA).
T, Endoh, A, Yagihashi, N, Uehara, D, Kobayashi, N, Tsuji, M, Nakamura, S, Hayashi, N, Fujii, N, Watanabe   +8 more
openaire   +3 more sources

Consider the midden

Inscriptions, 2021
Those who read the essay may be reminded of A.R. Ammon's poem, “Garbage” which a correspondant recently called to my attention. The overlap is coincidental; at time of writing, I was ignorant of that work. This essay investigates meanings of an old term:
David Ritchie
doaj  

Spoligtyping e polimorfismo do gene pncA: Um cenário em duas etapas para o diagnóstico de Mycobacterium bovis em Portugal

Revista Portuguesa de Pneumologia, 2005
Resumo: O diagnóstico diferencial do Mycobacterium bovis é importante no controlo da transmissão para a população humana e também no tratamento da doença, visto que o M. bovis é naturalmente resistente à pirazinamida.
Suzana David, Clara Portugal, Abílio Antunes, Ana Calado, Ângela Cardoso, Vanessa Barros, Luísa Sancho, José Germano de Sousa   +7 more
doaj   +1 more source

Prevalence and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Southern China

BMC Infectious Diseases, 2017
Background Pyrazinamide (PZA) plays a unique role in the treatment for multidrug-resistant tuberculosis (MDR-TB) in both first- and second-line regimens.
Yu Pang, Damian Zhu, Huiwen Zheng, Jing Shen, Yan Hu, Jie Liu, Yanlin Zhao   +6 more
doaj   +1 more source

Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia

BMC Infectious Diseases, 2017
The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights the need for more effective control strategies. A new regimen to treat MDR-TB that includes pyrazinamide (PZA) is currently being evaluated and PZA resistance status will largely influence the success of current and future treatment strategies.
Sarah Sengstake, Indra L Bergval, Anja R Schuitema, Jessica L de Beer, Jody Phelan, Rina de Zwaan, Taane G Clark, Dick van Soolingen, Richard M Anthony   +8 more
openaire   +5 more sources

Screening mutations in drug-resistant Mycobacterium tuberculosis strains in Yunnan, China

Journal of Infection and Public Health, 2017
Drug-resistant tuberculosis (DR-TB), especially multidrug-resistant tuberculosis (MDR-TB), is a serious medical and societal problem in China. The purpose of this study was to evaluate the mutation characteristics of drug-resistant Mycobacterium ...
Daoqun Li, Yuzhu Song, Cheng-Lin Zhang, Xiaofei Li, Xueshan Xia, A-Mei Zhang   +5 more
doaj   +1 more source

Comment on ‘Systematic Review and Meta‐Analysis of Protein Intake to Support Muscle Mass and Function in Healthy Adults’ by Nunes et al.—The Authors' Reply

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
Everson A. Nunes, Daniel Tomé, Sandra Naranjo‐Modad, Diana Sherifali, Claire Gaudichon, Stuart M. Phillips, the authors   +6 more
wiley   +1 more source

Stumbling on Dover Beach

Inscriptions, 2022
This is the third in a series of essays, linked thoughts about change over time.  In the space of very few years in world historical terms, English beaches and wave-like rolling hills were transformed.
David Ritchie
doaj  

Resistance To First-Line Antituberculosis Drugs And Prevalence Of pncA Mutations In Clinical Isolates Of Mycobacterium tuberculosis From Zunyi, Guizhou Province Of China

Infection and Drug Resistance, 2019
Zhimin Cao,1 Yuanbo Lan,1 Ling Chen,1 Min Xiang,1 Zhiyuan Peng,1 Jianyong Zhang,1 Hong Zhang1,2 1Tuberculosis Division, Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, People ...
Cao Z, Lan Y, Chen L, Xiang M, Peng Z, Zhang J, Zhang H   +6 more
doaj  

Monosodium Glutamate Supplementation Improves Bone Status in Mice Under Moderate Protein Restriction

JBMR Plus, 2019
Adequate protein intake during development is critical to ensure optimal bone gain and to attain a higher peak bone mass later. Using a mild protein restriction model in Balb/C mice consuming 6% of their total energy intake as soy protein (LP‐SOY)—for ...
Anne Blais, Gael Y Rochefort, Manon Moreau, Juliane Calvez, Xin Wu, Hideki Matsumoto, François Blachier   +6 more
doaj   +1 more source