Results 81 to 90 of about 2,913 (168)

Consider the midden

open access: yesInscriptions, 2021
Those who read the essay may be reminded of A.R. Ammon's poem, “Garbage” which a correspondant recently called to my attention. The overlap is coincidental; at time of writing, I was ignorant of that work. This essay investigates meanings of an old term:
David Ritchie
doaj  

Spoligtyping e polimorfismo do gene pncA: Um cenário em duas etapas para o diagnóstico de Mycobacterium bovis em Portugal

open access: yesRevista Portuguesa de Pneumologia, 2005
Resumo: O diagnóstico diferencial do Mycobacterium bovis é importante no controlo da transmissão para a população humana e também no tratamento da doença, visto que o M. bovis é naturalmente resistente à pirazinamida.
Suzana David   +7 more
doaj   +1 more source

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda.

open access: yesPLoS ONE, 2020
INTRODUCTION:Susceptibility testing for pyrazinamide (PZA), a cornerstone anti-TB drug is not commonly done in Uganda because it is expensive and characterized with technical difficulties thus resistance to this drug is less studied.
Resty Naluyange   +5 more
doaj   +1 more source

Detection of Pyrazinamide-Resistant Mycobacteriumtuberculosis by PCR-SSCP of pncA Gene

open access: yesTuberculosis and Respiratory Diseases, 1998
Background : Recently the incidence of tuberculosis is increasing in many countries and control of the disease is further threatened by the emergence of multi-drug resistant tuberculosis. So rapid detection of drug resistance is very important. Pyrazinamide (PZA) is a first-line chemotherapeutic agent for tuberculosis.
Tae Sun Shim   +8 more
openaire   +1 more source

Prevalence and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Southern China

open access: yesBMC Infectious Diseases, 2017
Background Pyrazinamide (PZA) plays a unique role in the treatment for multidrug-resistant tuberculosis (MDR-TB) in both first- and second-line regimens.
Yu Pang   +6 more
doaj   +1 more source

Pyrazinamide resistance associated with pncA gene mutation in Mycobacterium tuberculosis in Japan

open access: yesEpidemiology and Infection, 2002
Thirty Japanese clinical isolates of Mycobacterium tuberculosis were analysed by pyrazinamide susceptibility testing and pyrazinamidase assay, as well as polymerase chain reaction for single-strand conformational polymorphism and direct sequencing of the gene encoding pyrazinamidase (pncA).
T, Endoh   +8 more
openaire   +3 more sources

Screening mutations in drug-resistant Mycobacterium tuberculosis strains in Yunnan, China

open access: yesJournal of Infection and Public Health, 2017
Drug-resistant tuberculosis (DR-TB), especially multidrug-resistant tuberculosis (MDR-TB), is a serious medical and societal problem in China. The purpose of this study was to evaluate the mutation characteristics of drug-resistant Mycobacterium ...
Daoqun Li   +5 more
doaj   +1 more source

Stumbling on Dover Beach

open access: yesInscriptions, 2022
This is the third in a series of essays, linked thoughts about change over time.  In the space of very few years in world historical terms, English beaches and wave-like rolling hills were transformed.
David Ritchie
doaj  

Resistance To First-Line Antituberculosis Drugs And Prevalence Of pncA Mutations In Clinical Isolates Of Mycobacterium tuberculosis From Zunyi, Guizhou Province Of China

open access: yesInfection and Drug Resistance, 2019
Zhimin Cao,1 Yuanbo Lan,1 Ling Chen,1 Min Xiang,1 Zhiyuan Peng,1 Jianyong Zhang,1 Hong Zhang1,2 1Tuberculosis Division, Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, People ...
Cao Z   +6 more
doaj  

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