Results 71 to 80 of about 6,468 (198)

Fundamental Symmetries and Conservation Laws [PDF]

, 2009
I discuss recent progress in low-energy tests of symmetries and conservation laws, including parity nonconservation in atoms and nuclei, electric dipole moment tests of time-reversal invariance, beta-decay correlation studies, and decays violating ...
Adelberger, Adelberger, Auerbach, Bennett, Desplanques, Dobaczewski, Erler, Gorelov, Griffith, Haxton, Paradisi, Phillips, Porsev, Raidal, Sushkov, W.C. Haxton, Wood, Young, Zhu   +18 more
core   +1 more source

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

Infection and Drug Resistance, 2020
Jie Shi, Ruyue Su, Danwei Zheng, Yankun Zhu, Xiaoguang Ma, Shaohua Wang, Hui Li, Dingyong Sun Henan Province Center for Disease Control and Prevention, Zhengzhou, Henan Province, People’s Republic of ChinaCorrespondence: Jie Shi; Dingyong Sun Tel ...
Shi J, Su R, Zheng D, Zhu Y, Ma X, Wang S, Li H, Sun D   +7 more
doaj  

Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan

BMC Infectious Diseases, 2019
Background Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB).
Muhammad Tahir khan, Shaukat Iqbal Malik, Sajid Ali, Nayyer Masood, Tariq Nadeem, Anwar Sheed Khan, Muhammad Tanvir Afzal   +6 more
doaj   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G., Briers, Yves, Danis‐Wlodarczyk, Katarzyna, Drulis‐Kawa, Zuzanna, Jang, Ho Bin, Lavigne, Rob, Lood, Cédric, Noben, Jean‐Paul, Noort, Vera, Vandenheuvel, Dieter   +9 more
core   +1 more source

Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)‐N’‐Benzylidenepyrazine‐2‐Carbohydrazides and their Derivatives

ChemMedChem, Volume 20, Issue 18, September 25, 2025.
(E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides with 2‐OH, 2,3‐diOH or 2,4‐diOH substitution exhibit good antimycobacterial or antiproliferative activity, and iron chelation similar to salicylaldehyde isonicotinoyl hydrazone (SIH). A series of 33 (E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides and their derivatives were synthesized and tested for biological ...
Priam‐Amedeo Houngbedji, Daria Elżbieta Nawrot, Ondřej Janďourek, Klára Konečná, Martin Novák, Pavla Paterová, Pavel Bárta, Martina Hrast Rambaher, Eva Novotná, Carlo Castellano, Matteo Mori, Fiorella Meneghetti, Monika Záhorszká, Jana Korduláková, Jan Zitko   +14 more
wiley   +1 more source

Dietary Studies, Guidelines and Recommendations: Limited Nutrient Deficiency Risks and Significant Modelled Health Benefits in French Adults Following a More Plant-Based Diet

Proceedings
There is a current trend towards plant-based diets in Western countries. These diets have been associated with long-term health benefits but could limit the adequacy of some indispensable nutrients.
Pauline Mombert, Jean-François Huneau, Juhui Wang, Jeanne-Marie Membré, François Mariotti   +4 more
doaj   +1 more source

Characterization of pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis in Brazil [PDF]

Antimicrobial Agents and Chemotherapy, 2005
ABSTRACT In this study the nucleotide sequence of the pncA gene from 59 Mycobacterium tuberculosis clinical isolates was analyzed. Mutations in the pncA gene were identified in 29 of 40 pyrazinamide-resistant isolates, and no pyrazinamidase activity was ...
Vívian de F Sumnienski, Rodrigues, Maria Alice, Telles, Marta Osório, Ribeiro, Patrícia Izquierdo, Cafrune, Maria Lucia Rosa, Rossetti, Arnaldo, Zaha   +5 more
openaire   +3 more sources

Rapid colorimetric testing for pyrazinamide susceptibility of M. tuberculosis by a PCR-based in-vitro synthesized pyrazinamidase method. [PDF]

PLoS ONE, 2011
Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug. But PZA susceptibility test is challenging because PZA activity is optimal only in an acid environment that inhibits the growth of M. tuberculosis.
Man Zhou, Xuelei Geng, Jun Chen, Xude Wang, Dianbing Wang, Jiaoyu Deng, Zhiping Zhang, Weihua Wang, Xian-En Zhang, Hongping Wei   +9 more
doaj   +1 more source

First-Principles Structural, Mechanical, and Thermodynamic Calculations of the Negative Thermal Expansion Compound Zr2(WO4)(PO4)2

, 2018
The negative thermal expansion (NTE) material Zr2(WO4)(PO4)2 has been investigated for the first time within the framework of the density functional perturbation theory (DFPT).
Bryan, Charles R., Dingreville, Remi, Gordon, Margaret E., Greathouse, Jeffrey A., Kim, Eunja, Weck, Philippe F.   +5 more
core   +2 more sources

Elucidation of Beta-Oxidation Pathways in Ralstonia Eutropha H16 by Examination of Global Gene Expression [PDF]

, 2010
Ralstonia eutropha H16 is capable of growth and polyhydroxyalkanoate production on plant oils and fatty acids. However, little is known about the triacylglycerol and fatty acid degradation pathways of this bacterium. We compare whole-cell gene expression
Brigham, Christopher J., Budde, Charles F., Holder, Jason W., Mahan, Alison E., Rha, ChoKyun, Sinskey, Anthony J., Zeng, Qiandong   +6 more
core   +2 more sources